公开(公告)号：EP0851876B1

公开(公告)日：2004-06-30

申请号：EP96929619.3

申请日：1996-08-23

申请人： Rural Patent Svenska AB

发明人： LÖNNROTH, Ivar ,  LANGE, Stefan ,  JOHANSSON, Eva ,  JENNISCHE, Eva ,  LÖNNROTH, Christina

IPC分类号： C07K14/575 ,  A23K1/165 ,  A61K38/22

CPC分类号： C07K14/47 ,  A23K20/147 ,  A61K38/00 ,  C07K14/575 ,  Y02A50/471

摘要： A new recombinant protein called Antisecretory Factor (rAF) and homologues and peptide fragments thereof are described. The protein and the homologues and fragments thereof are useful for normalizing pathological fluid transport and/or inflammatory reactions in animals including humans. Antibodics against AF or homologues or fragments thereof are described. Nucleic acids coding for the protein or for homologues or fragments thereof are also described as well as vectors and hosts comprising the nucleic acids. The rAF and homologues and fragments thereof could be used for immunodetection, as feed additive for growing animals and as antidiarrheal and drugs against diseases involving edema, dehydration and/or inflammation.

公开(公告)号：EP0851876A1

公开(公告)日：1998-07-08

申请号：EP96929619.0

申请日：1996-08-23

申请人： Rural Patent Svenska AB

发明人： LÖNNROTH, Ivar ,  LANGE, Stefan ,  JOHANSSON, Eva ,  JENNISCHE, Eva ,  LÖNNROTH, Christina

IPC分类号： C12N15 ,  A23K1 ,  A61K31 ,  A61K38 ,  A61P1 ,  A61P3 ,  A61P29 ,  C07K14 ,  C07K16 ,  C12N5 ,  C12P21 ,  C12Q1 ,  C12R1

CPC分类号： C07K14/47 ,  A23K20/147 ,  A61K38/00 ,  C07K14/575 ,  Y02A50/471

摘要： A new recombinant protein called Antisecretory Factor (rAF) and homologues and peptide fragments thereof are described. The protein and the homologues and fragments thereof are useful for normalizing pathological fluid transport and/or inflammatory reactions in animals including humans. Antibodics against AF or homologues or fragments thereof are described. Nucleic acids coding for the protein or for homologues or fragments thereof are also described as well as vectors and hosts comprising the nucleic acids. The rAF and homologues and fragments thereof could be used for immunodetection, as feed additive for growing animals and as antidiarrheal and drugs against diseases involving edema, dehydration and/or inflammation.