HYDROLYZED CELLULOSE GRANULATIONS FOR PHARMACEUTICALS
    3.
    发明公开
    HYDROLYZED CELLULOSE GRANULATIONS FOR PHARMACEUTICALS 失效
    水解纤维素粒子药品

    公开(公告)号:EP0942715A4

    公开(公告)日:2006-01-18

    申请号:EP97918661

    申请日:1997-04-15

    IPC分类号: A61K9/16 A61K9/20

    CPC分类号: A61K9/2054

    摘要: The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.