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1.发明授权NEUE VITAMIN D-DERIVATE MIT CYCLOPROPYLRINGEN IN DEN SEITENKETTEN, VERFAHREN UND ZWISCHENPRODUKTE ZU IHRER HERSTELLUNG SOWIE IHRE VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN 有权与CYCLOPROPYLRINGEN IN侧链，方法以及它们的生产中间产品和它们用于药品生产的新维生素D衍生物
公开(公告)号：EP1025082B1
公开(公告)日：2003-05-02
申请号：EP98954292.3
申请日：1998-09-29
发明人： STEINMEYER, Andreas , NEEF, Günter , KIRSCH, Gerald , SCHWARZ, Katica , WIESINGER, Herbert , HABEREY, Martin , FÄHNRICH, Marianne , LANGER, Gernot
IPC分类号： C07C401/00 , A61K31/59
CPC分类号： C07C401/00 , A61K31/59 , A61K38/13 , A61K39/395 , A61K31/445 , A61K31/435 , A61K2300/00
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2.发明公开NEUE VITAMIN D-DERIVATE MIT CYCLOPROPYLRINGEN IN DEN SEITENKETTEN, VERFAHREN UND ZWISCHENPRODUKTE ZU IHRER HERSTELLUNG SOWIE IHRE VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN 有权与CYCLOPROPYLRINGEN IN侧链，方法以及它们的生产中间产品和它们用于药品生产的新维生素D衍生物
公开(公告)号：EP1025082A1
公开(公告)日：2000-08-09
申请号：EP98954292.3
申请日：1998-09-29
发明人： STEINMEYER, Andreas , NEEF, Günter , KIRSCH, Gerald , SCHWARZ, Katica , WIESINGER, Herbert , HABEREY, Martin , FÄHNRICH, Marianne , LANGER, Gernot
IPC分类号： C07C401/00 , A61K31/59
CPC分类号： C07C401/00 , A61K31/59 , A61K38/13 , A61K39/395 , A61K31/445 , A61K31/435 , A61K2300/00
摘要： The invention relates to novel vitamin D derivatives of general formula (I), a method for the production thereof, intermediate products of the method and the utilization of vitamin D derivatives for producing medicaments.
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3.发明授权
公开(公告)号：EP1210327B1
公开(公告)日：2006-01-18
申请号：EP00962278.8
申请日：2000-07-24
IPC分类号： C07C401/00
CPC分类号： B21C25/10 , B21C25/02 , C07C401/00 , C07D235/12 , C07D263/32 , C07D277/24 , C07D307/80 , C07D333/16 , C07D333/22 , Y02P20/55
摘要： The invention relates to vitamin D derivatives of the formula (I), wherein Z is an optionally substituted carbocyclic or heterocyclic, optionally aromatic or heteroaromatic 5- or 6-membered ring or an optionally substituted condensed ring structure that consists of a 5-membered and a 6-membered ring or of two 6-membered rings, and Q, R1-R4, X1-X2 and Y1-Y3 have the meanings given in the description. The invention further relates to a method for their production, to the use of said derivatives in the preparation of medicaments, and to a method for producing compounds of the formula (Iia), wherein E represents any side chain, and R7, R8, Y2, Y3 and Y5 have the meanings given in the description. The invention also relates to the intermediates of both methods.
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4.发明公开
公开(公告)号：EP1210327A2
公开(公告)日：2002-06-05
申请号：EP00962278.8
申请日：2000-07-24
IPC分类号： C07C401/00
CPC分类号： B21C25/10 , B21C25/02 , C07C401/00 , C07D235/12 , C07D263/32 , C07D277/24 , C07D307/80 , C07D333/16 , C07D333/22 , Y02P20/55
摘要： The invention relates to vitamin D derivatives of the formula (I), wherein Z is an optionally substituted carbocyclic or heterocyclic, optionally aromatic or heteroaromatic 5- or 6-membered ring or an optionally substituted condensed ring structure that consists of a 5-membered and a 6-membered ring or of two 6-membered rings, and Q, R1-R4, X1-X2 and Y1-Y3 have the meanings given in the description. The invention further relates to a method for their production, to the use of said derivatives in the preparation of medicaments, and to a method for producing compounds of the formula (Iia), wherein E represents any side chain, and R7, R8, Y2, Y3 and Y5 have the meanings given in the description. The invention also relates to the intermediates of both methods.
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公开(公告)号：EP1042335A1
公开(公告)日：2000-10-11
申请号：EP98966616.9
申请日：1998-12-16
发明人： STEINMEYER, Andreas , NEEF, Günter , KIRSCH, Gerald , SCHWARZ, Katica , WIESINGER, Herbert , HABEREY, Martin , FÄHNRICH, Marianne , LANGER, Gernot
IPC分类号： C07F9/40 , A61K31/66 , C07F9/53 , C07C401/00 , C07F9/38
CPC分类号： C07C401/00 , C07F9/383 , C07F9/386 , C07F9/4018 , C07F9/404 , C07F9/405 , C07F9/532
摘要： The invention relates to novel vitamin D derivatives of general formula (I), a method for the production thereof, intermediate products of the method as well as the utilization thereof for producing medicaments.
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