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1.发明公开Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation 失效双环化合物，它们作为药物，它们的生产和中间体及其制备的用途。
公开(公告)号：EP0302303A2
公开(公告)日：1989-02-08
申请号：EP88111666.9
申请日：1988-07-20
申请人： SCHERING CORPORATION
IPC分类号： C07D471/04 , C07D215/38 , A61K31/47 , A61K31/495
CPC分类号： C07D471/04 , C07D215/36 , C07D453/02
摘要： Bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents and in the treatment of hyperproliferative skin disease. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed. Many of the compounds are novel; inventive methods for their preparation and for the preparation of intermediates, are also disclosed.
摘要翻译： 双环化合物是游离缺失盘适用作抗过敏，抗炎和/或细胞保护剂和过度增生性皮肤疾病的治疗中是有用的。 因此药物组合物和治疗用人测试的化合物的方法是游离缺失盘。 许多化合物是新的; 本发明的方法对于它们的制备和对中间体的制备，被游离缺失盘。
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公开(公告)号：EP0533342A1
公开(公告)日：1993-03-24
申请号：EP92307344.9
申请日：1992-08-11
申请人： SCHERING CORPORATION
IPC分类号： C07D215/48 , C07D213/82 , C07C237/22 , C07D237/28 , C07D241/44 , C07D311/66 , C07D475/04 , C07D401/12 , C07D471/04 , C07D417/12
CPC分类号： C07D213/81 , A61K38/00 , C07C271/44 , C07C311/19 , C07C323/61 , C07C323/62 , C07C2601/08 , C07C2603/24 , C07D209/20 , C07D213/82 , C07D213/89 , C07D215/48 , C07D215/60 , C07D231/12 , C07D233/56 , C07D237/28 , C07D241/44 , C07D249/08 , C07D311/66 , C07D401/06 , C07D401/12 , C07D417/12 , C07D471/04 , C07D475/04 , C07K5/021 , C07K5/06139
摘要： Compounds of formula
wherein Ar, W, Z, Q, R₁, U, and T are as set forth herein, are described. These compounds, are active as agents against retroviruses and in particular against HIV.摘要翻译： 描述了其中Ar，W，Z，Q，R 1，U和T如本文所述的式
的化合物。 这些化合物作为抗逆转录病毒药物，特别是抗HIV药物是有效的。 -
3.发明公开Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation 失效双相化合物，它们作为药物的使用，其制备和中间体在其制备中有用
公开(公告)号：EP0302303A3
公开(公告)日：1989-05-24
申请号：EP88111666.9
申请日：1988-07-20
申请人： SCHERING CORPORATION
IPC分类号： C07D471/04 , C07D215/38 , A61K31/47 , A61K31/495
CPC分类号： C07D471/04 , C07D215/36 , C07D453/02
摘要： Bicyclic compounds are disclosed which are useful as anti-allergic, anti-inflammatory and/or cytoprotective agents and in the treatment of hyperproliferative skin disease. Pharmaceutical compositions and methods of treatment employing such compounds are also disclosed. Many of the compounds are novel; inventive methods for their preparation and for the preparation of intermediates, are also disclosed.
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