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公开(公告)号:EP0180615B1
公开(公告)日:1995-04-05
申请号:EP85902274.1
申请日:1985-04-16
申请人: SCIOS NOVA INC.
发明人: JOHNSON, Lorin, K. , ATLAS, Steven, A. , McCARTHY, Brian, J. , LARAGH, John, H. , LEWICKI, John, A.
CPC分类号: C12N15/85 , A61K38/00 , C07K14/58 , C07K14/582 , C07K2319/02 , C07K2319/036 , C07K2319/50 , C07K2319/75 , C12N15/70 , C12N15/81 , C12N2830/00 , C12N2830/002 , C12N2830/15 , C12N2830/55 , C12N2830/85
摘要: Methods and compositions for inducing natriuresis, diuresis and vasodilatation in mammalian hosts by administering atrial natriuretic/vasodilator polypeptides to said host. Also provided are methods for producing such polypeptides, and antibodies which are capable of recognizing and specifically binding to them.
摘要翻译: 通过向所述宿主施用心房钠尿素/血管舒张因子多肽在哺乳动物宿主中诱导利尿钠尿症,利尿和血管舒张的方法和组合物。 还提供了生产这些多肽的方法和能够识别并特异性结合它们的抗体。