公开(公告)号：EP0986757A4

公开(公告)日：2004-08-25

申请号：EP98928894

申请日：1998-06-04

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E

IPC: A61B5/00 ,  G01N33/53 ,  G01N33/66 ,  G01N33/68 ,  G01N33/542 ,  A61K49/00

CPC classification number: G01N33/6842 ,  A61B5/14532 ,  A61B5/1455 ,  G01N33/5308 ,  G01N33/66 ,  G01N33/68 ,  G01N2400/00 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/815 ,  Y10S436/827 ,  Y10T436/104998 ,  Y10T436/144444

Abstract: A method of evaluating a carbohydrate in a sample. The method includes providing a low valency carbohydrate binding ligand, providing a glycoconjugate which includes a label, and a carbohydrate moiety, contacting the low valency carbohydrate binding ligand and the glycoconjugate with the sample, determining the extent of binding of the low valency carbohydrate binding ligand with the glycoconjugate, the binding of the low valency carbohydrate binding ligand with the glycoconjugate being correlated with the amount of carbohydrate in the sample.

公开(公告)号：EP0649476A4

公开(公告)日：1997-05-07

申请号：EP93916805

申请日：1993-06-28

Applicant: SENSOR TECHNOLOGIES INC

Inventor： CHICK WILLIAM L ,  WOLF DAVID E ,  CARDULLO RICHARD A

IPC: C12Q1/68 ,  G01N33/52 ,  G01N33/58

CPC classification number: C12Q1/6818 ,  C12Q1/6825 ,  G01N33/52 ,  G01N33/582 ,  C12Q2565/107 ,  C12Q2563/107

Abstract: An in vivo method and apparatus for detecting an analyte in an individual. A sensor that includes a fluorescence reagent is placed in communication with the body fluids of the individual suspected of containing the analyte in such a way that once in place said sensor does not exit the skin of the individual. The sensor is configured to retain the fluorescence reagent while allowing analyte to diffuse into and out of said sensor. The sensor is illuminated transdermally, and the fluorescence from the fluorescence reagent associated with the presence of the analyte is measured.

公开(公告)号：EP1546675A4

公开(公告)日：2008-03-26

申请号：EP03767274

申请日：2003-08-01

Applicant: SENSOR TECHNOLOGIES INC

Inventor： WOLF DAVID E ,  BULSECO DYLAN A

IPC: G01N33/58 ,  C12M1/00 ,  C12M1/34 ,  C12N15/09 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/68 ,  C12Q1/70 ,  G01J3/44 ,  G01J3/457 ,  G01N21/64 ,  G01N21/78

CPC classification number: G01N21/6428 ,  G01J3/4406 ,  G01J3/457 ,  G01N21/645 ,  G01N33/582 ,  G01N2021/6417 ,  G01N2021/6482 ,  G01N2021/6484

Abstract: The invention features a method of assaying for the interaction of a probe and an unknown target, said method including a) exciting a sample with radiation, the sample including at least one unknown target, at least one probe, and at least one fluorescent tag, b) measuring the fluorescence from a subvolume of the sample, and c) analyzing the fluctuations of the fluorescence.