-
1.发明授权MODIFIED MAXADILAN PROTEIN, ITS PREPARATION AND USE, AND DNA ENCODING THE PROTEIN 失效改进maxadilan蛋白质，它的生产和使用，编码蛋白的DNA
公开(公告)号：EP0713532B1
公开(公告)日：2000-02-02
申请号：EP94924128.5
申请日：1994-08-05
IPC分类号： C12N15/62 , C07K14/435 , C12N15/12 , A61K38/17
CPC分类号： C07K14/43577 , A61K38/00 , C07K2319/00
摘要： A modified maxadilan protein exhibits higher biological activity than native maxadilan from the sand fly Lutzomyia longipalpis. A modified maxadilan fusion protein contains a thrombin cleavage site. This enables the production of the modified maxadilan as a fusion protein and recovery of the modified maxadilan after digestion with thrombin. The modified maxadilan is a potent vasodilator.
-
公开(公告)号：EP0900383A1
公开(公告)日：1999-03-10
申请号：EP97919648.0
申请日：1997-04-23
CPC分类号： G01N33/6842 , A61K38/00 , C07K14/47 , C07K14/57563 , G01N33/68
摘要： This specification relates to use of peptides having a specific affinity to subtype 1 of PACAP (pituitary adenylate cyclase activating polypeptide) receptors, particularly MAX (67 amino acids), NSP (61 amino acids) and M 65 (46 amino acids). MAX and NSP act as agonists to PACAP type 1 receptors, and M 65 acts as an antagonist to PACAP type 1 receptors.
-
3.发明公开MODIFIED MAXADILAN PROTEIN, ITS PREPARATION AND USE, AND DNA ENCODING THE PROTEIN 失效改进MOXADILAN蛋白，它的生产和使用，编码蛋白的DNA
公开(公告)号：EP0713532A1
公开(公告)日：1996-05-29
申请号：EP94924128.0
申请日：1994-08-05
CPC分类号： C07K14/43577 , A61K38/00 , C07K2319/00
摘要： A modified maxadilan protein exhibits higher biological activity than native maxadilan from the sand fly Lutzomyia longipalpis. A modified maxadilan fusion protein contains a thrombin cleavage site. This enables the production of the modified maxadilan as a fusion protein and recovery of the modified maxadilan after digestion with thrombin. The modified maxadilan is a potent vasodilator.
-
公开(公告)号：EP0900383B1
公开(公告)日：2003-03-26
申请号：EP97919648.2
申请日：1997-04-23
IPC分类号： G01N33/68 , G01N33/567 , G01N33/50
CPC分类号： G01N33/6842 , A61K38/00 , C07K14/47 , C07K14/57563 , G01N33/68
摘要： This specification relates to use of peptides having a specific affinity to subtype 1 of PACAP (pituitary adenylate cyclase activating polypeptide) receptors, particularly MAX (67 amino acids), NSP (61 amino acids) and M 65 (46 amino acids). MAX and NSP act as agonists to PACAP type 1 receptors, and M 65 acts as an antagonist to PACAP type 1 receptors.
-
公开(公告)号：EP0480048A1
公开(公告)日：1992-04-15
申请号：EP91906510.2
申请日：1991-03-29
摘要： An improved process for purifying a polypeptide with a packing for high-performance liquid chromatography, which comprises preteating polypeptides produced by various cells into a given state, adjusting the pH of an aqueous solution of the polypeptides to fall within a specified range to thereby remove contaminants by precipitation, and treating the remaining solution with a packing for reversed-phase high-performance liquid chromatography.
摘要翻译： 一种改进的用于高效液相色谱法用于填充多肽的方法，其包括将各种细胞产生的多肽提取到给定状态，调节多肽水溶液的pH落在规定范围内，从而除去污染物 通过沉淀，并用用于反相高效液相色谱的填料处理剩余的溶液。
-
公开(公告)号：EP0480048B1
公开(公告)日：1997-02-05
申请号：EP91906510.2
申请日：1991-03-29
IPC分类号： C07K1/00 , C07K1/14 , C07K14/585
摘要： An improved process for purifying a polypeptide with a packing for high-performance liquid chromatography, which comprises preteating polypeptides produced by various cells into a given state, adjusting the pH of an aqueous solution of the polypeptides to fall within a specified range to thereby remove contaminants by precipitation, and treating the remaining solution with a packing for reversed-phase high-performance liquid chromatography.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.015 秒)
