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公开(公告)号：EP1379237A2
公开(公告)日：2004-01-14
申请号：EP02736525.3
申请日：2002-03-28
IPC分类号： A61K31/40 , A61K31/445 , A61K31/55 , C07D401/10 , C07D403/10
CPC分类号： C07D401/12 , C07D207/14 , C07D211/58 , C07D403/12
摘要： The present invention relates to pyrrolidine sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
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公开(公告)号：EP1246619A1
公开(公告)日：2002-10-09
申请号：EP00990246.1
申请日：2000-12-19
发明人： DHANAK, Dashyant , KNIGHT, Steven, David , WARREN, Gregory, Lee , JIN, Jian , WIDDOWSON, Katherine, L. , KEENAN, Richard, McCulloch
IPC分类号： A61K31/34
CPC分类号： C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D409/14
摘要： The present invention relates to pyrrolidines, pharmaceutical compositions containing them and their use as antagonists of urotensin II.
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公开(公告)号：EP1379519A1
公开(公告)日：2004-01-14
申请号：EP02728588.1
申请日：2002-03-28
IPC分类号： C07D401/02 , C07D403/02 , A61K31/55 , A61K31/495 , A61K31/50 , A61P9/00
CPC分类号： C07D401/12 , A61K31/497 , C07D403/12
摘要： The present invention relates to pyrrolidine sulfonamide sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
摘要翻译： 本发明涉及吡咯烷磺酰胺磺酰胺，含有它们的药物组合物以及它们作为尿压素II拮抗剂的用途。
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公开(公告)号：EP1379503A1
公开(公告)日：2004-01-14
申请号：EP02725377.2
申请日：2002-03-28
IPC分类号： C07D211/00 , C07D401/02 , C07D403/02 , A61K31/55 , A61K31/445 , A61K31/40 , A61P9/00
CPC分类号： C07D409/14
摘要： The present invention relates to pyrrolidine sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
摘要翻译： 本发明涉及吡咯烷磺酰胺，含有它们的药物组合物以及它们作为尿压素II拮抗剂的用途。
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公开(公告)号：EP1244452A1
公开(公告)日：2002-10-02
申请号：EP00986598.1
申请日：2000-12-19
IPC分类号： A61K31/501 , A61K31/4025 , A61K31/4523 , A61K31/5377 , C07D207/10 , C07D211/56 , C07D401/10
CPC分类号： C07D401/10 , C07D207/14 , C07D211/56
摘要： The present invention relates to pyrrolyl and pyridyl derivatives, pharmaceutical compositions containing them and their use as inhibitors of urotensin II.
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公开(公告)号：EP1381365A1
公开(公告)日：2004-01-21
申请号：EP02757820.2
申请日：2002-03-28
IPC分类号： A61K31/496 , C07D409/14
CPC分类号： C07D409/12
摘要： The present invention relates to pyrrolidine sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
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7.发明授权CARBOXAMIDE DERIVATES OF PYRROLIDINE AND PIPERIDINE AS UROTENSIN-II RECEPTOR ANTAGONISTS 有权的吡咯烷酰胺及其哌啶，尾加压素II受体拮抗剂
公开(公告)号：EP1244452B1
公开(公告)日：2003-09-17
申请号：EP00986598.1
申请日：2000-12-19
IPC分类号： A61K31/501 , C07D207/14 , C07D207/16 , C07D211/58 , C07D401/12 , C07D405/12 , A61K31/4025 , A61K31/4523 , A61K31/5377 , A61K31/4468 , A61P9/10
CPC分类号： C07D401/10 , C07D207/14 , C07D211/56
摘要： The present invention relates to pyrrolyl and pyridyl derivatives, pharmaceutical compositions containing them and their use as inhibitors of urotensin II.
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公开(公告)号：EP2037922A2
公开(公告)日：2009-03-25
申请号：EP07798915.0
申请日：2007-06-22
发明人： DUFFY, Kevin, J. , FITCH, Duke, M. , JIN, Jian , LIU, Ronggang , SHAW, Antony, N. , WIGGALL, Kenneth
IPC分类号： A61K31/47 , A61K31/495 , C07D487/08
CPC分类号： C07D239/60 , A61K31/515 , C07D239/22 , C07D239/54 , C07D239/62 , C07D401/04 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/10 , C07D413/06 , C07D413/10 , C07D417/10
摘要： The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
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公开(公告)号：EP1246619B1
公开(公告)日：2004-10-20
申请号：EP00990246.1
申请日：2000-12-19
发明人： DHANAK, Dashyant , KNIGHT, Steven, David , WARREN, Gregory, Lee , JIN, Jian , WIDDOWSON, Katherine, L. , KEENAN, Richard, McCulloch
IPC分类号： A61K31/34 , C07D409/12 , C07D207/14 , C07D403/12 , C07D405/12 , C07D401/12 , A61K31/40 , A61K31/415 , A61K31/47
CPC分类号： C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D409/14
摘要： The present invention relates to pyrrolidines, pharmaceutical compositions containing them and their use as antagonists of urotensin II.
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