公开(公告)号：EP1603570A4

公开(公告)日：2008-05-21

申请号：EP04715001

申请日：2004-02-26

申请人： SUGEN INC

发明人： CUI JINGJONG JEAN ,  ZHANG JENNIFER ,  HANAU CATHLEEN ELIZABETH ,  BHUMRALKAR DILIP ,  BOTROUS IRINY ,  CHU JI YU ,  FUNK LEE A ,  HARRIS JR G DAVIS ,  JIA LEI ,  JOHNSON JOANNE ,  KOLODZIEJ STEPHEN A ,  KUNG PEI-PEI ,  LI XIAOYUAN SHARON ,  LIN JASON QISHEN ,  MENG JERRY JIALUN ,  NAMBU MITCHELL DAVID ,  NELSON CHRISTOPHER G ,  PAIRISH MASON ALAN ,  SHEN HONG ,  TRAN-DUBE MICHELLE

IPC分类号： C07D213/73 ,  A61K20060101 ,  A61K31/44 ,  A61K31/496 ,  A61K31/4965 ,  A61K31/497 ,  A61P35/00 ,  C07D20060101 ,  C07D211/72 ,  C07D401/00 ,  C07D401/12 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D413/12 ,  C07D417/00 ,  C07D419/00

CPC分类号： C07D213/73 ,  A61K45/06 ,  C07D401/12 ,  C07D413/12

摘要： Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.