公开(公告)号：EP3191483A4

公开(公告)日：2018-04-18

申请号：EP15840696

申请日：2015-09-11

申请人： SUNSHINE LAKE PHARMA CO LTD

发明人： ZHANG YINGJUN ,  YU TIANZHU ,  LIU BING ,  ZHANG XIANGYU ,  ZHANG SHIGUO ,  CHENG CHANGCHUNG ,  ZHANG JIANCUN

IPC分类号： C07D471/04 ,  A61K31/405 ,  A61P43/00 ,  C07D209/14 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12

CPC分类号： C07D209/14 ,  A61K31/405 ,  A61K31/4375 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/498 ,  A61K45/06 ,  C07B2200/13 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D471/04

摘要： The compounds of Formula (I) which can be used as CRTH2 receptor antagonists are provided. The compounds of Formula (I) can be used in the treatment and prevention of asthma, allergic rhinitis and atopic dermatitis, as well as other diseases mediated by prostaglandin D2 (PGD2) at the CRTH2 receptor.