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1.发明公开METHOD OF PRODUCING GLYCOPROTEIN, AND VECTOR, KIT, INSECT ORGANISM AND INSECT CELLS 审中-公开VERFAHREN ZUR HERSTELLUNG EINES GLYKOPROTEINS UND VEKTOR，KIT，INSEKTENORGANISMUS UND INSEKTENZELLEN
公开(公告)号：EP3075857A1
公开(公告)日：2016-10-05
申请号：EP16163069.4
申请日：2016-03-31
申请人： SYSMEX CORPORATION
IPC分类号： C12N15/63 , C07K14/435 , C07K16/40 , C12P21/00
CPC分类号： C12P21/005 , C07K14/43563 , C07K14/43586 , C07K16/40 , C07K2317/14 , C07K2317/41 , C07K2317/76 , C12N9/16 , C12N15/63 , C12N2799/026 , C12Y301/03001
摘要： Disclosed is a method of producing a glycoprotein, the method including the steps of: introducing a gene encoding a desired protein and a gene encoding an antibody that inhibits a decomposing enzyme preventing formation of a desired complex-type sugar chain in the desired protein into an insect organism or insect cells; and obtaining a desired protein having a desired complex-type sugar chain from the insect organism or insect cells obtained in the introduction step.
摘要翻译： 公开了一种生产糖蛋白的方法，所述方法包括以下步骤：引入编码所需蛋白质的基因和编码抗体的基因，所述基因抑制分解酶，从而阻止所需蛋白质中所需的复合型糖链形成为所需蛋白质 昆虫生物或昆虫细胞; 并从引入步骤中获得的昆虫生物体或昆虫细胞获得具有期望的复合型糖链的所需蛋白质。
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公开(公告)号：EP4242660A1
公开(公告)日：2023-09-13
申请号：EP23160420.8
申请日：2023-03-07
申请人： SYSMEX CORPORATION
发明人： Kubo, Takuya , Suganuma, Masatoshi , Ishiki, Kengo
摘要： Disclosed is a reagent for measuring L-biotin, comprising an optically isomeric biotin-binding site and an azobenzene derivative represented by following formula (I):
wherein R 1 to R 10 are each independently a group selected from the group consisting of a hydrogen atom, a hydroxy group, a carboxy group, C1 to C6 dialkylamino groups having no substituent or a substituted group, C1 to C6 alkyl groups having no substituent or a substituted group, and C1 to C6 alkoxy groups having no substituent or a substituted group, provided that at least one of R 1 to R 5 is a hydroxy group or a C1 to C6 dialkylamino group having no substituent or a substituted group, and at least one of R 6 to R 10 is a carboxy group.-
公开(公告)号：EP3868838A3
公开(公告)日：2021-11-24
申请号：EP21154523.1
申请日：2021-02-01
发明人： Hara, Daiki , Motoki, Takafumi , Kazuta, Yuji , Norimine, Yoshihiko , Amino, Hiroyuki , Suganuma, Masatoshi , Fujiyama, Shingo , Yamashita, Kazuto , Okada, Masaya , Nishikawa, Yoichi , Iwanaga, Shigeki
摘要： Disclosed is: a fluorescent dye consisting of a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy. The fluorescent dye has formula (I):
wherein A represents an optionally substituted C4-C7 heterocyclic ring which contains an Si atom.-
公开(公告)号：EP3868838A2
公开(公告)日：2021-08-25
申请号：EP21154523.1
申请日：2021-02-01
发明人： Hara, Daiki , Motoki, Takafumi , Kazuta, Yuji , Norimine, Yoshihiko , Amino, Hiroyuki , Suganuma, Masatoshi , Fujiyama, Shingo , Yamashita, Kazuto , Okada, Masaya , Nishikawa, Yoichi , Iwanaga, Shigeki
摘要： Disclosed is: a fluorescent dye consisting of a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy. The fluorescent dye has formula (I):
wherein A represents an optionally substituted C4-C7 heterocyclic ring which contains an Si atom.-
公开(公告)号：EP3404038A1
公开(公告)日：2018-11-21
申请号：EP18173066.4
申请日：2018-05-18
申请人： SYSMEX CORPORATION
CPC分类号： C12Q1/485 , C07K2/00 , C07K14/00 , C12Y207/11022 , G01N33/5011 , G01N33/573 , G01N33/68 , G01N2333/91215 , G01N2333/916 , G01N2500/04
摘要： Disclosed is a cyclin-dependent kinase substrate including a polypeptide that contains an amino acid sequence represented by formula (1): R 1 -P (wherein R 1 represents a serine residue or a threonine residue, P represents a proline residue, "-" represents a single bond, and the left side represents the N-terminal side), and satisfies the following (al) and/or (bl): (al) the second amino acid residue counting from the proline residue toward the N-terminal side in the formula (1) is an aromatic amino acid residue, and/or (bl) at least two amino acid residues from the proline residue toward the C-terminal side in the formula (1) are acidic amino acid residues.
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