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公开(公告)号：EP3411020A1
公开(公告)日：2018-12-12
申请号：EP17747672.8
申请日：2017-01-24
发明人： CHO, Eui Hwan , CHOI, Sung-Ju , LEE, Sung-Woo , SHIN, Hee-Jong , KI, Min-Hyo , CHOI, Mee-Hwa , OH, Tae-Hoon
IPC分类号： A61K9/28 , A61K9/48 , A61K47/44 , A61K31/403
CPC分类号： A61K9/284 , A61K9/2866 , A61K31/403
摘要： Disclosed is an immediate-release carvedilol formulation, which is configured such that a coating layer including a polymer, wax, fatty acid and/or fatty acid ester is formed on the surface thereof. This formulation has improved madescent, and thus can exhibit high stability, in which the initial appearance of the formulation can be maintained without cracking or breaking even under storage conditions at high relative humidity.
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公开(公告)号：EP3355929A1
公开(公告)日：2018-08-08
申请号：EP16852119.3
申请日：2016-09-30
发明人： CHO, Eui-Hwan , CHOI, Sung-Ju , LEE, Sung-Woo , SHIN, Hee-Jong , KI, Min-Hyo , CHOI, Mee-Hwa , LEE, Dong-Ha
IPC分类号： A61K47/40 , A61K47/18 , A61K9/00 , A61K31/4704
CPC分类号： A61K47/40 , A61K9/0048 , A61K9/08 , A61K31/4704 , A61K47/02 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/22 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/44
摘要： An ophthalmic composition is provided that includes rebamipide and a method for preparing the same. The ophthalmic composition of maintains its transparency for a long time even in a physiologically neutral to weakly basic pH range that does not injure the cornea and conjunctiva of a patient suffering from dry eye and has improved stability so as not to be re-dispersed.
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