公开(公告)号：EP2167470B1

公开(公告)日：2011-03-16

申请号：EP08762666.9

申请日：2008-06-02

申请人： Sanofi-Aventis

发明人： SUSÁN, Edit ,  BOÉR, Kinga ,  KAPUI, Zoltán ,  TIMÁRI, Géza ,  BÁTORI, Sándor ,  SZLÁVIK, Zoltán ,  MIKUS, Endre ,  VARGÁNÉ SZEREDI, Judit ,  FINET, Michel ,  URBÁN SZABÓ, Katalin ,  SZABÓ, Tibor

IPC分类号： C07D215/58 ,  C07D471/04 ,  C07F7/22 ,  A61K31/4745 ,  A61P11/06 ,  A61P29/00

CPC分类号： C07D471/04

摘要： The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates,
N -oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof.

公开(公告)号：EP2167470A1

公开(公告)日：2010-03-31

申请号：EP08762666.9

申请日：2008-06-02

申请人： Sanofi-Aventis

发明人： SUSÁN, Edit ,  BOÉR, Kinga ,  KAPUI, Zoltán ,  TÍMÁRI, Géza ,  BÁTORI, Sándor ,  SZLÁVIK, Zoltán ,  MIKUS, Endre ,  VARGÁNÉ SZEREDI, Judit ,  FINET, Michel ,  URBÁN SZABÓ, Katalin ,  SZABÓ, Tibor

IPC分类号： C07D215/58 ,  C07D471/04 ,  C07F7/22 ,  A61K31/4745 ,  A61P11/06 ,  A61P29/00

CPC分类号： C07D471/04

摘要： The present invention relates to the adenosine A3 receptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates,
N -oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates,
N -oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof.