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1.发明授权VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2,3-DIAMINOPROPIONSÄUREDERIVATEN 有权VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2,3-DIAMINOPROPIONS-AUREDERIVATEN
公开(公告)号：EP1778627B1
公开(公告)日：2008-02-27
申请号：EP05758872.5
申请日：2005-06-28
发明人： RIEKE-ZAPP, Joerg , BILLEN, Guenter
IPC分类号： C07C271/22 , C07C233/85 , C07C233/83 , C07D213/74 , C07D277/42 , C07C231/18 , C07C269/06
CPC分类号： C07C227/32 , C07B2200/07 , C07C227/30 , C07C231/18 , C07C233/85 , C07C271/22 , C07D213/74 , C07D277/42 , C07C233/83
摘要： The invention relates to a method for producing enantiomeric form of 2, 3-diaminopropionic acid derivatives of formula (I) by asymmetric hydrogenation from compounds of formula (II).
摘要翻译： 本发明涉及通过式（II）化合物的不对称氢化制备式（I）的2,3-二氨基丙酸衍生物的对映体形式的方法。
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2.发明公开VERFAHREN ZUR HERSTELLUNG DER ENANTIOMEREN FORMEN VON 2,3-DIAMINOPROPIONSÄUREDERIVATEN 有权PROCESS FOR 2,3-DIAMINOPROPIONSÄUREDERIVATEN对映体形式制备
公开(公告)号：EP1778627A1
公开(公告)日：2007-05-02
申请号：EP05758872.5
申请日：2005-06-28
发明人： RIEKE-ZAPP, Joerg , BILLEN, Guenter
IPC分类号： C07C271/22 , C07C233/85 , C07C233/83 , C07D213/74 , C07D277/42 , C07C231/18 , C07C269/06
CPC分类号： C07C227/32 , C07B2200/07 , C07C227/30 , C07C231/18 , C07C233/85 , C07C271/22 , C07D213/74 , C07D277/42 , C07C233/83
摘要： The invention relates to a method for producing enantiomeric form of 2, 3-diaminopropionic acid derivatives of formula (I) by asymmetric hydrogenation from compounds of formula (II).
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3.发明公开VERFAHREN ZUR HERSTELLUNG VON (3-OXO-2,3-DIHYDRO-1H-ISOINDOL-1-Yl)-ACETYLGUANIDIN-DERIVATEN 有权用于生产（3-氧代-2,3-二氢-1H-异吲哚-1-基）方法-ACETYLGUANIDIN衍生物
公开(公告)号：EP1692105A1
公开(公告)日：2006-08-23
申请号：EP04803188.4
申请日：2004-11-19
发明人： SCHUBERT, Gerrit , RIEKE-ZAPP, Joerg , KEIL, Johannes , KLEEMANN, Heinz-Werner , HANNA, Reda , HUANG, Bao-Guo , WU, Xiao-Dong , GOURAUD, Yves
IPC分类号： C07D209/46 , C07C233/66
CPC分类号： C07D209/46
摘要： The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of racemates and to intermediate products of the inventive method.
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4.发明授权ACYL-4-CARBOXY-PHENYL-HARNSTOFFDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG 有权酰基4-羧基苯基脲衍生物，用于生产及其用途
公开(公告)号：EP1497262B1
公开(公告)日：2010-08-04
申请号：EP03712111.8
申请日：2003-03-28
发明人： DEFOSSA, Elisabeth , KADEREIT, Dieter , SCHOENAFINGER, Karl , KLABUNDE, Thomas , BURGER, Hans-Joerg , HERLING, Andreas , WENDT, Karl-Urlich , VON ROEDERN, Erich , ENHSEN, Alfons , RIEKE-ZAPP, Joerg
IPC分类号： C07C275/54 , C07D295/12 , A61K31/17 , A61P7/12
CPC分类号： C07D295/155 , C07C275/54
摘要： The invention relates to acyl-4-carboxyphenylurea derivatives, the physiologically-acceptable salts, physiologically-functional derivatives thereof and compounds of formula (I), where the groups have the given meanings, the physiologically acceptable salts and method for production thereof. Said compounds are suitable, for example, as anti-diabetics.
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5.发明授权VERFAHREN ZUR HERSTELLUNG VON (3-OXO-2,3-DIHYDRO-1H-ISOINDOL-1-Yl)-ACETYLGUANIDIN-DERIVATEN 有权用于生产（3-氧代-2,3-二氢-1H-异吲哚-1-基）方法-ACETYLGUANIDIN衍生物
公开(公告)号：EP1692105B1
公开(公告)日：2008-05-14
申请号：EP04803188.4
申请日：2004-11-19
发明人： SCHUBERT, Gerrit , RIEKE-ZAPP, Joerg , KEIL, Johannes , KLEEMANN, Heinz-Werner , HANNA, Reda , HUANG, Bao-Guo , WU, Xiao-Dong , GOURAUD, Yves
IPC分类号： C07D209/46 , C07C233/66
CPC分类号： C07D209/46
摘要： The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of racemates and to intermediate products of the inventive method.
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