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公开(公告)号：EP3760207A1
公开(公告)日：2021-01-06
申请号：EP19759990.5
申请日：2019-02-27
发明人： TAKAHASHI, Kyohei , ASADA, Hiroyuki , KAMIMURA, Asuka , MORISHIMA, Kenji , MOMOKAWA, Yusuke , ENDO, Kenichi
IPC分类号： A61K31/7072 , A61K9/08 , A61K9/10 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/42 , A61P27/02
摘要： Provided is an ophthalmic composition comprising diquafosol or a salt thereof and a cationic polymer, the cationic polymer being at least one selected from the group consisting of chitosan, a chitosan derivative, a cationic (meth)acrylate copolymer, a cationic silicone polymer, a diallyl quaternary ammonium salt-acrylamide copolymer, cationic hydrolyzed keratin, cationic hydrolyzed silk, cationic hydrolyzed collagen, cationic hydrolyzed casein, cationic hydrolyzed soy protein, a cationic vinylpyrrolidone copolymer, polyvinylpyrrolidone, a dimethyldiacrylammonium chloride homopolymer, an adipic acid-dimethylaminohydroxypropyldiethylenetriamine copolymer, an adipic acid-epoxypropyldiethylenetriamine copolymer and an acrylamide-β-methacryloyloxyethyltrimethylammoniummethyl sulfate copolymer.
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2.发明公开
公开(公告)号：EP3932488A1
公开(公告)日：2022-01-05
申请号：EP20763542.6
申请日：2020-02-26
摘要： Provided is an ophthalmic composition comprising diquafosol or a salt thereof, a vinyl-based polymer and a cellulose-based polymer. Also provided is an agent for prevention or treatment of dry eyes, comprising diquafosol or a salt thereof, a vinyl-based polymer and a cellulose-based polymer. These solution-type aqueous eye drop for treatment of dry eye each comprises diquafosol sodium with a concentration of 3%(w/v), hydroxyethyl cellulose and polyvinylpyrrolidone having a K value of 30, and is characterized in that a single dose of 1 to 2 drops is administered by eye drop three times per day.
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3.发明公开THERAPEUTIC AGENT FOR DRY EYE CHARACTERIZED BY BEING TO BE DROPPED INTO EYE OF DRY EYE PATIENT WEARING SOFT CONTACT LENS 审中-公开干眼症治疗剂的特征在于将干眼病患者戴在眼睛上，戴上柔软隐形眼镜
公开(公告)号：EP3305301A1
公开(公告)日：2018-04-11
申请号：EP16803503.8
申请日：2016-06-03
IPC分类号： A61K31/7084 , A61P27/04
CPC分类号： A61K31/7084 , A61K9/0048 , A61K47/10 , A61K47/14 , A61P27/04
摘要： The present invention addressed the problem of finding an agent for treating onset and/or exacerbation of dry eye symptom caused by wearing soft contact lenses.
An ophthalmic solution, which comprises diquafosol tetrasodium salt and is free from benzalkonium chloride, treats onset and/or exacerbation of dry eye symptom caused by wearing soft contact lenses.摘要翻译： 本发明解决了寻找治疗由于佩戴软性隐形眼镜引起的干眼症状的发作和/或恶化的药剂的问题。 包含地夸磷索四钠盐且不含苯扎氯铵的眼用溶液治疗由于佩戴软性隐形眼镜而引起的干眼症的发作和/或恶化。
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