-
1.发明公开Monoclonal antibodies against human interleukin-4 and hybridomas producing the same 失效MonoklonaleAntikörpergegen menschliches Interleukin-4 und Hybridomen，die sie produzieren。
公开(公告)号：EP0314402A2
公开(公告)日：1989-05-03
申请号：EP88309926.9
申请日：1988-10-21
CPC分类号： C12N15/66 , A61K38/00 , C07K14/5406 , C07K16/247 , C07K2319/02 , C12N15/70
摘要： Monoclonal antibodies are provided which are specific for human interleukin-4. Kits and methods are also provided for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
摘要翻译： 提供了对人白细胞介素-4有特异性的单克隆抗体。 还提供了用于检测，测量和免疫人白细胞介素-4并用于阻断人白细胞介素-4的生物活性的试剂盒和方法。
-
2.发明授权Expression vectors for the production of human Granulocyte-Macrophage Colony Stimulation Factor in a mammalian cell host(18.05.92) 失效表达载体在马马里细胞宿主体内产生人粒细胞巨噬细胞集落刺激因子（18.05.92）
公开(公告)号：EP0299782B1
公开(公告)日：1993-04-07
申请号：EP88306486.7
申请日：1988-07-15
CPC分类号： C07K14/535 , A61K38/00
-
3.发明公开
公开(公告)号：EP0299782A2
公开(公告)日：1989-01-18
申请号：EP88306486.7
申请日：1988-07-15
CPC分类号： C07K14/535 , A61K38/00
摘要： Human granulocyte-macrophage colony stimulating factor (GM-CSF) polypeptides are provided, as well as methods for synthesizing conformationally and antigenically neutral muteins. The disclosed GM-CSFs promote growth and development of various hematopoietic lineages, and may be useful in treating conditions involving depressed blood cell populations and/or depressed blood cell regeneration, such as myeloid hypoplasia, chronic infections, and hematopoiesis after bone marrow transplantation. The invention also includes a novel mammalian expression vector.
摘要翻译： 提供人粒细胞 - 巨噬细胞集落刺激因子（GM-CSF）多肽，以及合成和抗原性中性突变蛋白的合成方法。 所公开的GM-CSF促进各种造血谱系的生长和发育，并且可用于治疗涉及抑制血细胞群体和/或抑制血细胞再生的病症，例如骨髓移植后骨髓发育不全，慢性感染和造血。 本发明还包括一种新型的哺乳动物表达载体。
-
4.发明公开
公开(公告)号：EP0299782A3
公开(公告)日：1989-08-09
申请号：EP88306486.7
申请日：1988-07-15
CPC分类号： C07K14/535 , A61K38/00
摘要： Human granulocyte-macrophage colony stimulating factor (GM-CSF) polypeptides are provided, as well as methods for synthesizing conformationally and antigenically neutral muteins. The disclosed GM-CSFs promote growth and development of various hematopoietic lineages, and may be useful in treating conditions involving depressed blood cell populations and/or depressed blood cell regeneration, such as myeloid hypoplasia, chronic infections, and hematopoiesis after bone marrow transplantation. The invention also includes a novel mammalian expression vector.
-
5.发明公开Monoclonal antibodies against human interleukin-4 and hybridomas producing the same 失效人类白细胞介素-4的单克隆抗体及其生产的杂交瘤
公开(公告)号：EP0314402A3
公开(公告)日：1989-06-07
申请号：EP88309926.9
申请日：1988-10-21
CPC分类号： C12N15/66 , A61K38/00 , C07K14/5406 , C07K16/247 , C07K2319/02 , C12N15/70
摘要： Monoclonal antibodies are provided which are specific for human interleukin-4. Kits and methods are also provided for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
-
-
-
-
搜索结果
5 条记录 (耗时 0.012 秒)
