专利检索 ap:("Schering Corporation") AND inv:"DAI, Xing" 第 1 页

1.

发明公开
SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS 有权
标题翻译： SPIRO-IMIDAZOLONDERIVATE ALS GLUCAGONREZEPTORANTAGONISTEN

公开(公告)号：EP2350020A1

公开(公告)日：2011-08-03

申请号：EP09741076.5

申请日：2009-09-30

申请人： Schering Corporation

发明人： STAMFORD, Andrew , MILLER, Michael, W. , DEMONG, Duane, Eugene , GREENLEE, William, J. , KOZLOWSKI, Joseph, A. , LAVEY, Brian, J. , WONG, Michael, K.C. , YU, Wensheng , DAI, Xing , YANG, De-Yi , ZHOU, Guowei

IPC分类号： C07D235/02 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/14 , C07D403/12 , C07D491/10 , A61K31/4184 , A61K31/4188 , A61K31/4439 , A61K31/4453 , A61K31/47

CPC分类号： C07D235/02 , A61K31/4184 , A61K45/06 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/14 , C07D403/12 , C07D491/10 , A61K2300/00

摘要： The present invention relates to compounds of the general formula: (I) wherein ring A, ring B, R
1 , R
3 , Z, L
1 , and L
2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.

2.

发明公开
BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS MODULATORS OF THE ACTIVITY OF GPR119 有权
标题翻译：双环杂环衍生物及其视为活动GPR 119的调节剂

公开(公告)号：EP2217596A2

公开(公告)日：2010-08-18

申请号：EP08832779.6

申请日：2008-08-20

申请人： Schering Corporation

发明人： XIA, Yan , BOYLE, Craig, D. , GREENLEE, William, J. , CHACKALAMANNIL, Samuel , JAYNE, Charles, Lee , STAMFORD, Andrew, W. , DAI, Xing , HARRIS, Joel, M. , NEUSTADT, Bernard, R. , NEELAMKAVIL, Santhosh, Francis , SHAH, Unmesh, G. , LANKIN, Claire, M. , LIU, Hong

IPC分类号： C07D451/06 , C07D471/08 , C07D498/08 , C07D487/08 , C07D491/08 , A61K31/46 , A61K31/439 , A61K31/506 , A61K31/537 , A61P3/00 , C07D401/14 , C07D495/08

CPC分类号： C07D451/06 , A61K31/439 , C07D401/14 , C07D451/14 , C07D471/08 , C07D487/08 , C07D491/08 , C07D495/08 , C07D498/08

摘要： The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.