公开(公告)号：EP1303487A1

公开(公告)日：2003-04-23

申请号：EP01959041.3

申请日：2001-07-19

申请人： Schering Corporation ,  CORVAS INTERNATIONAL, INC.

发明人： SAKESENA, Anil K. ,  GIRIJAVALLABHAN, Viyyoor, Moopil ,  BOGEN, Stephane, L. ,  LOVEY, Raymond, G. ,  JAO, Edwin, E. ,  BENNETT, Frank ,  MC CORMICK, Jinping, L. ,  WANG, Haiyan ,  PIKE, Russell, E. ,  LIU, Yi-Tsung ,  CHAN, Tin-Yau ,  ZHU, Zhaoning ,  ARASAPPAN, Ashok ,  CHEN, Kevin, X. ,  VENKATRAMAN, Srikanth ,  PAREKH, Tejal, N. ,  PINTO, Patrick, A. ,  SANTHANAM, Bama ,  NJOROGE, F., George ,  GANGULY, Ashit K. ,  VACCARO, Henry A. ,  KEMP, Scott Jeffrey ,  LEVY, Odile Esther ,  LIM-WILBY, Marguerita ,  TAMURA, Susan Y.

IPC分类号： C07D209/02 ,  C07D211/04 ,  C07D233/56 ,  C07D317/10 ,  C07D319/04 ,  C07D339/02 ,  C07D339/08 ,  C07C229/00 ,  C07C233/05 ,  C07C271/08 ,  C07C271/32 ,  A61K31/16 ,  A61K31/27 ,  A61K31/195 ,  A61K31/357 ,  A61K31/385 ,  A61K31/403 ,  A61K31/445 ,  A61K31/4164

CPC分类号： C07K7/06 ,  A61K31/16 ,  A61K31/195 ,  A61K31/27 ,  A61K31/357 ,  A61K31/385 ,  A61K31/403 ,  A61K31/4164 ,  A61K31/445 ,  A61K38/05 ,  C07C205/51 ,  C07K5/101 ,  C07K7/02 ,  A61K2300/00

摘要： The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.