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公开(公告)号:EP2461812B1
公开(公告)日:2014-01-01
申请号:EP10739941.2
申请日:2010-08-05
申请人: SciPharm SàRL
IPC分类号: A61K31/557 , A61K31/5585 , A61P11/00
CPC分类号: A61K31/5575 , A61K9/0019 , A61K9/0053 , A61K9/007 , A61K31/5578 , A61K31/5585
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公开(公告)号:EP2461812A1
公开(公告)日:2012-06-13
申请号:EP10739941.2
申请日:2010-08-05
申请人: SciPharm SàRL
IPC分类号: A61K31/557 , A61K31/5585 , A61P11/00
CPC分类号: A61K31/5575 , A61K9/0019 , A61K9/0053 , A61K9/007 , A61K31/5578 , A61K31/5585
摘要: The present invention provides compositions comprising a prostacyclin or prostacyclin analogue, or a pharmaceutically acceptable salt thereof for use in preventing or treating cystic fibrosis. The invention also provides the use of a kit comprising a prostacyclin or prostacyclin analogue for treating or preventing a condition associated with cystic fibrosis in a subject.
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公开(公告)号:EP2672957B1
公开(公告)日:2016-11-02
申请号:EP12704027.7
申请日:2012-02-03
申请人: SciPharm SàRL
IPC分类号: A61K31/437 , A61K31/44 , A61K45/06 , A61K31/5575 , A61K31/5578 , A61K31/5585 , A61P11/00 , A61P43/00
CPC分类号: A61K31/192 , A61K31/4166 , A61K31/437 , A61K31/44 , A61K31/5575 , A61K31/5578 , A61K31/5585 , A61K45/06 , A61K2300/00
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公开(公告)号:EP2672957A1
公开(公告)日:2013-12-18
申请号:EP12704027.7
申请日:2012-02-03
申请人: SciPharm SàRL
IPC分类号: A61K9/00 , A61K9/28 , A61K9/48 , A61K31/192 , A61K31/343 , A61K31/37 , A61K31/4015 , A61K31/404 , A61K31/4174 , A61K31/427 , A61K31/437 , A61K31/44 , A61K31/444 , A61K31/472 , A61K31/498
CPC分类号: A61K31/192 , A61K31/4166 , A61K31/437 , A61K31/44 , A61K31/5575 , A61K31/5578 , A61K31/5585 , A61K45/06 , A61K2300/00
摘要: The present invention provides a composition comprising at least one prostacyclin or prostacyclin analogue or a pharmaceutically acceptable salt thereof and at least one phosphodiesterase (PDE) 4inhibitor and optionally a further PDE inhibitor for use in preventing or treating cystic fibrosis by selectively increasing the cAMP levels in bronchoepithelial cells.
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