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    FIELD OF VIEW MATCHING IN A VISUAL PROSTHESIS
    4.
    发明公开
    FIELD OF VIEW MATCHING IN A VISUAL PROSTHESIS 审中-公开
    ANPASSUNG DES SEHFELDS IN EINER SEHPROTHESE

    公开(公告)号：EP2155320A2

    公开(公告)日：2010-02-24

    申请号：EP08714149.5

    申请日：2008-01-31

    申请人： Second Sight Medical Products, Inc.

    发明人： GREENBERG, Robert, J. ,  ROY, Arup ,  CASPL, Avraham, L. ,  MCMAHON, Matthew, J.

    IPC分类号： A61N1/05 ,  A61N1/36 ,  A61F9/08

    CPC分类号： A61N1/36046 ,  A61B3/1005 ,  A61B5/4836 ,  A61N1/0543

    摘要： A visual prosthesis apparatus including a video capture device for capturing a video image, a video processing unit associated with the video capture device, the video processing unit configured to convert the video image to stimulation patterns, and a stimulation system configured to stimulate subject's neural tissue based on the stimulation patterns, wherein the stimulation system provides a span of visual angle matched to the subject's neural tissue being stimulated.

    摘要翻译： 一种视觉假体装置，包括用于捕获视频图像的视频捕获装置，与视频捕捉装置相关联的视频处理单元，被配置为将视频图像转换为刺激模式的视频处理单元，以及被配置为刺激受试者的神经组织的刺激系统 基于刺激模式，其中所述刺激系统提供与被刺激的对象的神经组织匹配的视角跨度。

    SUB-THRESHOLD STIMULATION TO PRECONDITION NEURONS FOR SUPRA-THRESHOLD STIMULATION
    6.
    发明公开
    SUB-THRESHOLD STIMULATION TO PRECONDITION NEURONS FOR SUPRA-THRESHOLD STIMULATION 有权
    SUB-膨胀来刺激预处理神经元超膨胀刺激

    公开(公告)号：EP1937352A2

    公开(公告)日：2008-07-02

    申请号：EP06825064.6

    申请日：2006-09-19

    申请人： Second Sight Medical Products, Inc.

    发明人： GREENBERG, Robert, J. ,  MCMAHON, Matthew, J.

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36046 ,  A61N1/0543

    摘要： In order to generate the smallest phosphenes possible, it is advantageous to selectively stimulate smaller cells. By hyperpolarizing the somas of the large cells selectively with sub-threshold anodic 'pre-pulse' stimuli (making them more difficult to stimulate) and then selectively depolarize the smaller cells one can selectively stimulate smaller cells. Alternatively, one can hyperpolarize the dendrites of the cells with larger dendritic fields by applying sub-threshold anodic currents on surrounding electrodes and then depolarizing the smaller cells in the center. Further, one can manipulate the phases of an individual biphasic wave to affect selective stimulation resulting in more focal responses. It is possible to increase resolution with the 'pre-pulse' described above. One can also effect resolution by modifying the pulse order of the cathodic and anodic phases. Further, one can isolate the effect of the phases by separating them in time (long inter-phase interval) or by making one of the phases long and low amplitude - always keeping equal total charge for the two phases. As an example, one can preferentially stimulate smaller ganglion cells by providing a longer sub-threshold anodic pulse balanced with a shorter supra-threshold cathodic pulse. Preferentially stimulating the smaller ganglion cells will allow stimulation of different brightness levels while maintaining high spatial resolution.

    RETINAL PROSTHESIS WITH A NEW CONFIGURATION
    10.
    发明公开
    RETINAL PROSTHESIS WITH A NEW CONFIGURATION 有权
    RETINA-PROTHESE MIT NEUER KONFIGURATION

    公开(公告)号：EP1926526A1

    公开(公告)日：2008-06-04

    申请号：EP06814978.0

    申请日：2006-09-19

    申请人： Second Sight Medical Products, Inc.

    发明人： GREENBERG, Robert, J. ,  MCMAHON, Matthew, J. ,  LITTLE, James, Singleton ,  MCCLURE, Kelly, H. ,  MECH, Brian, V. ,  TALBOT, Neil, Hamiton ,  NEYSMITH, Jordan, M.

    IPC分类号： A61N1/36

    CPC分类号： A61N1/0543 ,  A61N1/025 ,  A61N1/36046 ,  A61N1/37229 ,  H05K1/028 ,  H05K1/0281 ,  H05K1/118 ,  H05K3/0014 ,  H05K3/28 ,  H05K2201/0133 ,  H05K2201/09018 ,  H05K2201/09909 ,  H05K2203/1105 ,  H05K2203/1476 ,  H05K2203/302

    摘要： Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, and cortical stimulation, and many related purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue.

    摘要翻译： 聚合物材料可用作神经刺激的电极阵列体。 它们特别适用于视网膜刺激以产生人造视觉，耳蜗刺激以产生人造听觉和皮质刺激以及许多相关目的。 通过电极阵列对视网膜或其他神经组织施加的压力至关重要。 太小的压力会导致电阻增加以及电场分散。 太多的压力可能会阻止血液流动。 通常的柔性电路制造技术通常需要使柔性电路电极阵列平坦。 由于神经组织几乎从不平坦，平面阵列必然会施加不均匀的压力。 此外，柔性电路聚合物阵列的边缘可以是尖锐的并切割精细的神经组织。 通过将适量的热应用于完整的阵列，可以诱导曲线。 对于热塑性聚合物，可以进一步有利的是在多个模具中反复加热柔性电路，每个模具具有减小的半径。 此外，沿着边缘添加材料是有利的。 在柔性电路阵列中提供折叠或扭曲是更有利的。 可以在折叠内部和外部添加附加材料以促进与组织的良好密封。