公开(公告)号：EP4286850A1

公开(公告)日：2023-12-06

申请号：EP22745826.2

申请日：2022-01-25

申请人： Sekisui Medical Co., Ltd.

发明人： FUJIMURA Kengo ,  NOMOTO Daigo ,  SHIMIZU Tomo ,  KORA Yuki

IPC分类号： G01N33/543

摘要： An object of the invention is to suppress non-specific reaction in an immunoreaction measurement method. An immunoassay method characterized by conducting immunoreaction in the presence of an anti-C3 antibody in a method for measuring an analyte in a sample immunologically is provided. Moreover, a method for suppressing non-specific reaction in a method for immunologically measuring an analyte in a sample which is characterized by conducting immunoreaction in the presence of an anti-C3 antibody is provided.

公开(公告)号：EP4067904A1

公开(公告)日：2022-10-05

申请号：EP20893719.3

申请日：2020-11-27

申请人： Sekisui Medical Co., Ltd.

发明人： ASAI Tomohide ,  TANAKA Yoshihiro ,  SUZUKI Ikumi ,  SEO Satoko ,  USUI Tomoyuki ,  SHIMIZU Tomo ,  MIYAZAKI Osamu

IPC分类号： G01N33/53 ,  G01N33/543

摘要： A problem to be solved by the invention is to improve the sensitivity of measurement of an analyte in a sample by a sandwich immunoassay. The sensitivity can be improved significantly in a sandwich immunoassay using a first antibody and a second antibody when one or both of the first antibody and the second antibody are a mixture of a monoclonal antibody recognizing a linear epitope and a monoclonal antibody recognizing a conformational epitope.

公开(公告)号：EP3778916A1

公开(公告)日：2021-02-17

申请号：EP19777053.0

申请日：2019-04-01

申请人： Sekisui Medical Co., Ltd.

发明人： MIURA Tomohiro ,  SHIMIZU Tomo ,  MIYAZAKI Osamu

IPC分类号： C12P21/06 ,  C07K14/78 ,  C07K14/82 ,  C07K16/30 ,  C12P21/08 ,  C12Q1/34 ,  G01N33/53

摘要： What is required is a method of producing, without treating a glycoprotein in a biological sample with a denaturing agent in advance, a selectively binding material, which specifically reacts with a glycan of a glycoprotein, a selectively binding material such as antibody thus produced by the method, and a method of specifically detecting a glycoprotein by using the selectively binding material.
In order to solve the problems, the present invention produces a selectively binding material specifically reactive with a glycan of a glycoprotein by treating the glycoprotein with a glycan-specific glycan-cleaving enzyme.