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1.
公开(公告)号:EP1620455B1
公开(公告)日:2011-11-30
申请号:EP04729374.1
申请日:2004-04-24
发明人: KANG, Heonjoong 412-305 Saetbyeol maeul apartment , HAM, Jungyeob, 123-404, Gwanak dream town , CHIN, Jungwook, 101-301 Miwon apartment
IPC分类号: C07J13/00
CPC分类号: C07J13/007 , C07J1/0011 , C07J21/006 , C07J31/006 , C07J33/007 , C07J71/001 , C07J75/00
摘要: The present invention relates to a method for selective preparing 4,17 (20)-E-pregnadiene-3,16-dione (E-guggulsterone) of the formula (III) and 4,17 (20)-Z-pregnadiene-3,16-dione (Z-guggulsterone) of the formula (IV) having an effect of lowering the elevated low density lipoprotein (LDL) and high levels of the cholesterol effectively, and elevating the low levels of the high density lipoprotein (HDL) from a easy-available steroid of the following formula (I). Also, the present invention provides a method for preparation of the compound of the above formula (II).