公开(公告)号：EP4428239A1

公开(公告)日：2024-09-11

申请号：EP22887213.1

申请日：2022-10-31

申请人： Shionogi & Co., Ltd

发明人： YOSHIKAWA, Mai ,  ONODA, Junji ,  NAKAMORI, Daiki ,  TAKAHASHI, Tatsuya ,  KASAI, Erika

IPC分类号： C12N15/13 ,  A61K39/395 ,  A61P17/04 ,  A61P25/04 ,  A61P29/00 ,  A61P29/02 ,  C07K16/18 ,  C07K16/28 ,  C12N15/63

CPC分类号： A61K39/395 ,  A61P17/04 ,  A61P25/04 ,  A61P29/00 ,  A61P29/02 ,  C07K16/00 ,  C07K16/18 ,  C07K16/28 ,  C12N15/63

摘要： Objective of the present invention is to provide a novel Nav1.7 monoclonal antibody. It discloses a Nav1.7 monoclonal antibody or its antibody fragment, having specific six CDRs or specific heavy chain variable regions/light chain variable regions. The monoclonal antibody and the like can be used for treating or preventing pain, pruritus and so on.