公开(公告)号：EP3936509A1

公开(公告)日：2022-01-12

申请号：EP20771072.4

申请日：2020-03-06

申请人： Shouyao Holdings (Beijing) Co., Ltd.

发明人： WANG, Jinghan ,  YAO, Jinsuo ,  DUAN, Xiaowei ,  YUAN, Baokun ,  LIU, Xijie ,  JIAO, Nan ,  MIN, Wangyang ,  SUN, Ying ,  LU, Chang ,  SUN, Yinghui ,  ZHANG, Jiuqing ,  JI, Yeling ,  HOU, Deng

IPC分类号： C07D519/00 ,  C07D471/14 ,  A61K31/438 ,  A61K31/4995 ,  A61K31/4375 ,  A61K31/496 ,  A61K31/499 ,  A61K31/5386 ,  A61K31/5377 ,  A61K31/541 ,  A61P35/00

摘要： The invention relates to an FGFR4 kinase inhibitor, and the preparation method and use thereof. The invention relates to a compound of Formula I, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof, and use thereof in the manufacture of a medicament for the treatment of an FGFR4 mediated disease.