公开(公告)号：EP3141894A1

公开(公告)日：2017-03-15

申请号：EP15789114.4

申请日：2015-03-19

申请人： Showa Denko K.K.

发明人： KONDO, Hideyuki ,  SASUGA, Junji ,  SHUKUYA, Takayuki

IPC分类号： G01N30/72 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/88

CPC分类号： G01N30/52 ,  B01D15/305 ,  B01D15/363 ,  B01D15/3847 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/6052 ,  G01N30/72 ,  G01N30/7233 ,  G01N30/88 ,  G01N30/96

摘要： A mass spectrometry method by a liquid chromatograph-mass spectrometer that can detect an organic acid with high sensitivity by retaining, separating and eluting the organic acid without adding any nonvolatile substance to a mobile phase and without receiving any restriction of a ratio of a water-soluble organic solvent, and an analytical column are provided. The mass spectrometry method is a mass spectrometry method for an organic acid by a liquid chromatograph-mass spectrometer, wherein a column packed with a hydrophilic polymer having an anion-exchange group is used, and as a mobile phase, a water-soluble organic solvent-water mixed solution is used. The analytical column is a column for liquid chromatography for an organic acid, in which a polyether ether ketone (PEEK) resin housing for liquid chromatography is packed with a hydrophilic polymer having an anion-exchange group.

摘要翻译： 通过液相色谱 - 质谱质谱的方法，可以检测到没有有机酸与通过保留，分离和不添加任何非挥发性的物质的移动相和没有接收到拒水的比率的任何限制洗脱有机酸高灵敏度 提供水溶性有机溶剂，并分析柱。 质谱分析方法是通过液相色谱 - 质谱仪，worin使用填充有具有阴离子交换基团的亲水性聚合物的柱对有机酸的质谱法，和作为流动相，水溶性有机溶剂 - 水用于混合溶液。 分析柱是用于液相色谱的柱在有机酸中，其中用于液相色谱的聚醚醚酮（PEEK）树脂壳体填充有具有阴离子交换基团的亲水性聚合物。

公开(公告)号：EP3112858A1

公开(公告)日：2017-01-04

申请号：EP15754822.3

申请日：2015-02-23

申请人： Showa Denko K.K.

发明人： NAKAJIMA, Naoya ,  OKADA, Yoshiji ,  KONDO, Hideyuki

IPC分类号： G01N30/88 ,  B01D15/08 ,  B01J20/24 ,  B01J20/34

CPC分类号： B01J20/24 ,  B01D15/305 ,  B01J20/265 ,  B01J20/286 ,  B01J20/289 ,  B01J20/291 ,  B01J20/34 ,  G01N30/48 ,  G01N30/482 ,  G01N30/60 ,  G01N30/88 ,  G01N33/02 ,  G01N2030/027

摘要： Apackingmaterial for liquidchromatography, which is excellent in durability, and a column for liquid chromatography, which is filled with the packing material, are provided. The packing material for liquid chromatography is characterized by comprising a hydrophilic resin containing a polyvinyl alcohol resin, to said hydrophilic resin an amino group represented by the formula (1) having been bonded through a spacer. In the formula (1), R 1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R 2 represents an alkyl group having 1 to 6 carbon atoms and having one or more hydroxyl groups, and represents a bonding position to the spacer.

摘要翻译： 提供耐久性优异的液相色谱用填充材料和填充有填充材料的液相色谱柱。 用于液相色谱的包装材料的特征在于包括含有聚乙烯醇树脂的亲水性树脂，所述亲水性树脂由通过间隔基键合的由式（1）表示的氨基。 式（1）中，R 1表示氢原子或碳原子数1〜4的烷基，R 2表示碳原子数1〜6的烷基，具有一个以上羟基，表示与 间隔物。

公开(公告)号：EP3112858B1

公开(公告)日：2018-05-23

申请号：EP15754822.3

申请日：2015-02-23

申请人： Showa Denko K.K.

发明人： NAKAJIMA, Naoya ,  OKADA, Yoshiji ,  KONDO, Hideyuki

IPC分类号： G01N30/88 ,  G01N30/02 ,  G01N30/60 ,  G01N33/02 ,  B01D15/08 ,  B01D15/30 ,  B01J20/24 ,  B01J20/281 ,  B01J20/291 ,  B01J20/34

CPC分类号： B01J20/24 ,  B01D15/305 ,  B01J20/265 ,  B01J20/286 ,  B01J20/289 ,  B01J20/291 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/34 ,  G01N30/48 ,  G01N30/482 ,  G01N30/60 ,  G01N30/88 ,  G01N33/02 ,  G01N2030/027

摘要： Apackingmaterial for liquidchromatography, which is excellent in durability, and a column for liquid chromatography, which is filled with the packing material, are provided. The packing material for liquid chromatography is characterized by comprising a hydrophilic resin containing a polyvinyl alcohol resin, to said hydrophilic resin an amino group represented by the formula (1) having been bonded through a spacer. In the formula (1), R 1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R 2 represents an alkyl group having 1 to 6 carbon atoms and having one or more hydroxyl groups, and represents a bonding position to the spacer.