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1.发明公开COMPENSATION OF MOTION-RELATED ERROR IN A STREAM OF MOVING MIRCO-ENTITIES 有权运动误差的A POWER表征移动单位MICRO
公开(公告)号：EP2732395A1
公开(公告)日：2014-05-21
申请号：EP12826436.3
申请日：2012-08-24
CPC分类号： G01N15/1404 , G01N15/1427 , G01N15/1429 , G01N15/1459 , G01N2015/1006 , G01N2015/1075 , G01N2015/1415 , G01N2015/1438 , G01N2015/1477 , G01N2015/149
摘要： Apparatus and methods for detecting, characterizing, and compensating motion-related error of moving micro-entities are described. Motion-related error may occur in streams of moving micro-entities, and may represent a deviation in and expected arrival time or an uncertainty in position of a micro-entity within the stream. Motion-related error of micro-entities is observed in a flow cytometer, e.g., as pulse jitter, and is found to have a functional dependence on a parameter of the system. The pulse jitter can be compensated, according to one embodiment, by adjusting data acquisition observation windows. For the flow cytometer, a reduction of pulse jitter can improve measurement accuracy, resolution of doublets, system throughput, and enable an increase in an interrogation region for probing the micro-entities.
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2.发明授权
公开(公告)号：EP2724144B1
公开(公告)日：2018-04-11
申请号：EP12826157.5
申请日：2012-08-24
CPC分类号： G01N15/1404 , G01N15/1427 , G01N15/1429 , G01N15/1459 , G01N2015/1006 , G01N2015/1075 , G01N2015/1415 , G01N2015/1438 , G01N2015/1477 , G01N2015/149
摘要： Apparatus and methods for detecting, characterizing, and compensating motion-related error of moving micro-entities are described. Motion-related error may occur in streams of moving micro-entities, and may represent a deviation in and expected arrival time or an uncertainty in position of a micro-entity within the stream. Motion-related error of micro-entities is observed in a flow cytometer, e.g., as pulse jitter, and is found to have a functional dependence on a parameter of the system. The pulse jitter can be compensated, according to one embodiment, by adjusting data acquisition observation windows. For the flow cytometer, a reduction of pulse jitter can improve measurement accuracy, resolution of doublets, system throughput, and enable an increase in an interrogation region for probing the micro-entities.
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3.发明授权
公开(公告)号：EP2732395B1
公开(公告)日：2018-04-04
申请号：EP12826436.3
申请日：2012-08-24
CPC分类号： G01N15/1404 , G01N15/1427 , G01N15/1429 , G01N15/1459 , G01N2015/1006 , G01N2015/1075 , G01N2015/1415 , G01N2015/1438 , G01N2015/1477 , G01N2015/149
摘要： Apparatus and methods for detecting, characterizing, and compensating motion-related error of moving micro-entities are described. Motion-related error may occur in streams of moving micro-entities, and may represent a deviation in and expected arrival time or an uncertainty in position of a micro-entity within the stream. Motion-related error of micro-entities is observed in a flow cytometer, e.g., as pulse jitter, and is found to have a functional dependence on a parameter of the system. The pulse jitter can be compensated, according to one embodiment, by adjusting data acquisition observation windows. For the flow cytometer, a reduction of pulse jitter can improve measurement accuracy, resolution of doublets, system throughput, and enable an increase in an interrogation region for probing the micro-entities.
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公开(公告)号：EP2456881A2
公开(公告)日：2012-05-30
申请号：EP10802787.1
申请日：2010-07-20
发明人： SHINODA, Masataka , DURACK, Gary
IPC分类号： C12Q1/02 , G01N33/483 , C12M1/34
CPC分类号： G01N15/1484 , G01N2015/1006 , G01N2015/149
摘要： Embodiments of the present disclosure generally include a method and apparatus for performing cytometry. Specifically, embodiments of the invention comprise apparatus for providing a sample fluid to a cytometry system comprising a cytometry chip and a holder. The cytometry chip is for channeling a sample fluid from a sample fluid port to an output channel. The holder is configured to retain the cytometry chip within the holder. The holder comprises an interface between the cytometry chip and at least one of a source of the sample fluid, a source of a sheath fluid or a source of electric charge. Embodiments of a method comprise using the apparatus to provide a sample fluid to a cytometry system.
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5.发明公开CHARACTERIZATION OF MOTION-RELATED ERROR IN A STREAM OF MOVING MICRO-ENTITIES 有权运动误差的A POWER移动单元MICRO表征
公开(公告)号：EP2724144A1
公开(公告)日：2014-04-30
申请号：EP12826157.5
申请日：2012-08-24
IPC分类号： G01N21/00
CPC分类号： G01N15/1404 , G01N15/1427 , G01N15/1429 , G01N15/1459 , G01N2015/1006 , G01N2015/1075 , G01N2015/1415 , G01N2015/1438 , G01N2015/1477 , G01N2015/149
摘要： Apparatus and methods for detecting, characterizing, and compensating motion-related error of moving micro-entities are described. Motion-related error may occur in streams of moving micro-entities, and may represent a deviation in and expected arrival time or an uncertainty in position of a micro-entity within the stream. Motion-related error of micro-entities is observed in a flow cytometer, e.g., as pulse jitter, and is found to have a functional dependence on a parameter of the system. The pulse jitter can be compensated, according to one embodiment, by adjusting data acquisition observation windows. For the flow cytometer, a reduction of pulse jitter can improve measurement accuracy, resolution of doublets, system throughput, and enable an increase in an interrogation region for probing the micro-entities.
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