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公开(公告)号：EP2147099B1
公开(公告)日：2018-08-08
申请号：EP08754990.3
申请日：2008-05-01
发明人： GLASS, John I. , ALPEROVICH, Nina , HUTCHINSON, Clyde A. III , LARTIGUE, Carole , MERRYMAN, Charles , SMITH, Hamilton O. , VASHEE, Sanjay , VENTER, Craig J.
CPC分类号： C12N15/10 , C12N15/1079 , C12N15/74
摘要： The presently disclosed invention relates to methods of installing a genome isolated from one species (the donor) into suitably prepared cells of a second species (the recipient). Introduction of the donor genetic material into the recipient host cell effectively converts the recipient host cell into a new cell that, as a result of the operation of the donated genetic material, is functionally classified as belonging to the genus and species of the donor genetic material.
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公开(公告)号：EP2147099A1
公开(公告)日：2010-01-27
申请号：EP08754990.3
申请日：2008-05-01
发明人： GLASS, John I. , ALPEROVICH, Nina , HUTCHINSON, Clyde A. III , LARTIGUE, Carole , MERRYMAN, Charles , SMITH, Hamilton O. , VASHEE, Sanjay , VENTER, J. Craig
CPC分类号： C12N15/10 , C12N15/1079 , C12N15/74
摘要： The presently disclosed invention relates to methods of installing a genome isolated from one species (the donor) into suitably prepared cells of a second species (the recipient). Introduction of the donor genetic material into the recipient host cell effectively converts the recipient host cell into a new cell that, as a result of the operation of the donated genetic material, is functionally classified as belonging to the genus and species of the donor genetic material.
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公开(公告)号：EP2542676A1
公开(公告)日：2013-01-09
申请号：EP10726723.9
申请日：2010-05-19
发明人： BENDERS, Gwynedd, A. , GLASS, John, I. , HUTCHISON, Clyde, A. , LARTIGUE, Carole , VASHEE, Sanjay , ALGIRE, Mikkel, A. , SMITH, Hamilton, O. , MERRYMAN, Charles, E. , NOSKOV, Vladimir, N. , CHUANG, Ray-yuan , GIBSON, Daniel, G. , VENTER, J. Craig
CPC分类号： C12N15/1079 , C12N15/1031 , C12N15/66 , C12N15/81
摘要： Compositions and methods are disclosed herein for cloning a synthetic or a semi-synthetic donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
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公开(公告)号：EP2403944A2
公开(公告)日：2012-01-11
申请号：EP10708854.4
申请日：2010-03-05
发明人： BENDERS, Gwynedd, A. , GLASS, John, I. , HUTCHISON, Clyde, A. , LARTIGUE, Carole , VASHEE, Sanjay , ALGIRE, Mikkel, A. , SMITH, Hamilton, O. , MERRYMAN, Charles, E. , NOSKOV, Vladimir, N. , CHUANG, Ray-Yuan , GIBSON, Daniel G. , VENTER, J., Craig
IPC分类号： C12N15/10
CPC分类号： C12N15/905 , C12N15/10 , C12N15/1031 , C12N15/1079 , C12N15/1093 , C12N15/81
摘要： Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
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公开(公告)号：EP3249045A1
公开(公告)日：2017-11-29
申请号：EP17177614.9
申请日：2010-03-05
发明人： BENDERS, Gwynedd A , GLASS, John I , HUTCHISON, Clyde A , LARTIGUE, Carole , VASHEE, Sanjay , ALGIRE, Mikkel A , SMITH, Hamilton O , MERRYMAN, Charles E , NOSKOV, Vladimir N , CHUANG, Ray-Yuan , GIBSON, Daniel G , VENTER, J Craig
IPC分类号： C12N15/10
CPC分类号： C12N15/905 , C12N15/10 , C12N15/1031 , C12N15/1079 , C12N15/1093 , C12N15/81
摘要： Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
摘要翻译： 本文公开了用于在异源宿主细胞中克隆供体基因组的组合物和方法。 在一个实施方案中，供体基因组可以在宿主细胞内进一步修饰。 可以从宿主细胞中进一步分离修饰的或未修饰的基因组并将其转移至受体细胞。 本文公开的方法可用于在更易处理的宿主细胞中改变来自难治性供体细胞的供体基因组。
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公开(公告)号：EP2403944B1
公开(公告)日：2017-06-28
申请号：EP10708854.4
申请日：2010-03-05
发明人： BENDERS, Gwynedd, A. , GLASS, John, I. , HUTCHISON, Clyde, A. , LARTIGUE, Carole , VASHEE, Sanjay , ALGIRE, Mikkel, A. , SMITH, Hamilton, O. , MERRYMAN, Charles, E. , NOSKOV, Vladimir, N. , CHUANG, Ray-Yuan , GIBSON, Daniel G. , VENTER, J., Craig
IPC分类号： C12N15/10
CPC分类号： C12N15/905 , C12N15/10 , C12N15/1031 , C12N15/1079 , C12N15/1093 , C12N15/81
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7.发明授权INSTALLATION OF GENOMES OR PARTIAL GENOMES INTO CELLS OR CELL-LIKE SYSTEMS 有权局部基因组的安装，基因组在细胞或细胞其他设备
公开(公告)号：EP1963515B1
公开(公告)日：2014-05-28
申请号：EP06851502.2
申请日：2006-12-22
发明人： GLASS, John I. , YOUNG, Lei , LARTIGUE, Carole , ASSAD-GARCIA, Nacyra , SMITH, Hamilton O. , HUTCHISON, Clyde , VENTER, J. Craig
CPC分类号： C12P21/02 , C12N2510/00
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