公开(公告)号：EP2260863A1

公开(公告)日：2010-12-15

申请号：EP09725208.4

申请日：2009-03-27

申请人： Takara Bio, Inc.

发明人： SANO, Mutsumi ,  AMEMOTO, Mayumi ,  DODO, Satsuki ,  KAWANO, Yasuhiro ,  KATO, Ikunoshin

IPC分类号： A61K39/395 ,  A61K31/711 ,  A61K48/00 ,  A61P31/04 ,  A61P31/06 ,  A61P43/00 ,  C07K16/12 ,  C12N15/02 ,  C12P21/08

CPC分类号： A61K31/711 ,  A61K2039/505 ,  C07K16/12 ,  C07K16/1232 ,  C07K2317/55 ,  C07K2317/76 ,  Y02A50/473 ,  Y02A50/481

摘要： Disclosed is a prophylactic or therapeutic agent for bacterial infectious diseases, which comprises an antibody capable of binding to a toxin or an antitoxin that constitutes a bacterial toxin-antitoxin system to inhibit the interaction between the toxin and the antitoxin or a gene for the antibody as an active ingredient.

摘要翻译： 公开了一种细菌感染性疾病的预防或治疗剂，其包含能够结合毒素或抗毒素的抗体，其构成细菌毒素 - 抗毒素系统以抑制毒素和抗毒素之间的相互作用或抗体的基因作为 活性成分。

公开(公告)号：EP1067196B1

公开(公告)日：2009-02-18

申请号：EP99910758.4

申请日：1999-03-30

申请人： TAKARA BIO INC.

发明人： KURITA, Toyohisa ,  IZU, Hiroyuki ,  SANO, Mutsumi ,  KATO, Ikunoshin

IPC分类号： C12P13/00 ,  C12P13/16

CPC分类号： C12P13/001

公开(公告)号：EP1707211A1

公开(公告)日：2006-10-04

申请号：EP04819454.2

申请日：2004-11-26

申请人： TAKARA BIO INC.

发明人： SANO, Mutsumi ,  IZU, Hiroyuki ,  IMAMURA, Mitsuo ,  OKAMOTO, Motoko ,  KURITA, Toyohisa ,  KATO, Ikunoshin

IPC分类号： A61K36/18 ,  A61K31/201 ,  A61K8/18 ,  A61K8/99 ,  A61P17/04 ,  A61P35/00 ,  A61P37/08 ,  A61P43/00 ,  A23L1/30 ,  C07C59/42

CPC分类号： A61K31/201 ,  A23L33/105 ,  A61K8/97 ,  A61K36/03 ,  A61K36/16 ,  A61K36/28 ,  A61K36/282 ,  A61K36/42 ,  A61K36/61 ,  A61K36/75 ,  A61K2800/782 ,  A61Q19/02 ,  C07C59/42

摘要： The present invention provides a ceramidase activity inhibitor which inhibits ceramidase activity, specifically neutral/alkaline ceramidase activity, characterized in that the inhibitor comprises, as an active ingredient, a processed product derived from at least one plant selected from the group consisting of plants belonging to Ginkgoaceae, plants belonging to Cucurbitaceae, plants belonging to Rutaceae, plants belonging to Laminariaceae, plants belonging to Myrtaceae and plants belonging to Compositae, and a medicament, a quasi-drug, cosmetics and a food, each comprising the inhibitor.

摘要翻译： 本发明提供了抑制神经酰胺酶活性，特别是中性/碱性神经酰胺糖酶活性的神经酰胺酶活性抑制剂，其特征在于，所述抑制剂包含作为活性成分的来自至少一种选自以下的植物的加工品：属于 银杏科，属于葫芦科的植物，属于芸香科的植物，属于藜科的植物，属于桃金娘科的植物和属于菊科的植物，以及药物，准药物，化妆品和食品，各自包含抑制剂。

公开(公告)号：EP1094114B1

公开(公告)日：2007-01-03

申请号：EP99926821.2

申请日：1999-06-25

申请人： TAKARA BIO INC.

发明人： UENO, Mitsuhiro ,  YOSHIOKA, Hirofumi ,  KONISHI, Haruko 407, Gurankoto-Rakuyo ,  HASHINO, Kimikazu ,  MORISHITA, Mio ,  CHONO, Hideto ,  MIYAMURA, Tsuyoshi ,  SANO, Mutsumi ,  ASADA, Kiyozo ,  FUJINAGA, Kei ,  KATO, Ikunoshin

IPC分类号： C12N15/86 ,  C07K14/78 ,  C12N15/87

CPC分类号： C12N15/86 ,  A61K48/00 ,  C12N2740/13043 ,  C12N2740/13045 ,  C12N2810/10 ,  C12N2810/80 ,  C12N2810/851 ,  C12N2810/859

摘要： Improved methods for transferring a gene into target cells by using a retrovirus, wherein the gene transfer efficiency is improved and the target cells are efficiently transformed by binding the retrovirus to a functional substance which is immobilized on a carrier and having an activity of binding to retroviruses followed by washing; using an antibody capable of specifically recognizing cells, laminin or a mannose-rich type sugar chain as a substance having an activity of binding to the target cells; pre-treating the target cells so as to activate transfferin receptor; or introducing a new functional group into the functional substance.

公开(公告)号：EP1310503A1

公开(公告)日：2003-05-14

申请号：EP01984490.1

申请日：2001-07-30

申请人： TAKARA BIO INC.

发明人： MIYAMURA, Tsuyoshi ,  EGASHIRA, Tomoe ,  SANO, Mutsumi ,  BENDIAK, Brad K. ,  KATO, Ikunoshin

IPC分类号： C07H1/00 ,  C07C243/10 ,  G01N33/58

CPC分类号： C07H5/04 ,  C07B2200/11

摘要： A process for producing hydrazinomonosaccharide derivatives and use of hydrazines in determining the structures of aldose and ketose monosaccharides located at the reducing ends of saccharides.

摘要翻译： 一种生产肼糖单体衍生物的方法，以及肼在确定糖类还原末端的醛糖和酮糖单糖的结构中的应用。