公开(公告)号：EP0919237A1

公开(公告)日：1999-06-02

申请号：EP97900470.2

申请日：1997-01-21

申请人： TAKARA SHUZO CO. LTD. ,  Research Institute for Glycotechnology

发明人： SAKAI, Takeshi, Research Inst. Glycotechnology ,  KITANO, Hideo, Research Inst. Glycotechnology ,  YU, Fu-gong, Research Inst. Glycotechnology ,  NAKAYAMA, Shinji, Research Inst. Glycotechnology ,  KOJIMA, Kaoru, Research Inst. Glycotechnology ,  KIMURA, Hitomi, Research Inst. Glycotechnology ,  NAKANISHI, Yoshikuni, ResearchInst.Glycotechnology ,  KATAYAMA, Kaoru, Research Inst. Glycotechnology ,  TOMINAGA, Takanari, Takara Shuzo Co., Ltd. ,  SHIMANAKA, Kazuo, Takara Shuzo Co., Ltd. ,  IKAI, Katsushige, Takara Shuzo Co., Ltd. ,  KATO, Ikunoshin, Research Inst. Glycotechnology

IPC分类号： A61K31/725 ,  C08B37/00

CPC分类号： C12Y302/01078 ,  A61K31/737 ,  C12N9/2494 ,  C12P19/14 ,  C12Y302/01044

摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

摘要翻译： 包含含有硫酸化岩藻糖的多糖和/或其降解产物的细胞凋亡诱导剂，抗癌药和制癌药以及通过使用含有硫酸化岩藻糖的多糖和/或降解产物诱导凋亡的方法 （一种或多种）作为活性成分。 一种降解酶，用于生产含硫酸化岩藻糖的多糖的降解产物。