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公开(公告)号：EP1826272A3
公开(公告)日：2008-12-03
申请号：EP07008180.7
申请日：1998-05-26
申请人： TAKARA BIO INC.
发明人： Takayama, Masanori Central Research Laboratories , Koyama, Nobuto Central Research Laboratories , Sakai, Takeshi Biotechnology Research Laboratories , Kato, Ikunoshin Central Research Laboratories
CPC分类号： C12N9/00 , C12N9/2402 , C12Y302/01044
摘要： An isolated gene having a DNA sequence coding for the polypeptide having a degrading activity of the sulfated-fucose-containing polysaccharide or having the functionally identical activity as above.
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公开(公告)号：EP1826272A2
公开(公告)日：2007-08-29
申请号：EP07008180.7
申请日：1998-05-26
申请人： TAKARA BIO INC.
发明人： Takayama, Masanori Central Research Laboratories , Koyama, Nobuto Central Research Laboratories , Sakai, Takeshi Biomedical Group , Kato, Ikunoshin Central Research Laboratories
IPC分类号： C12N15/56
CPC分类号： C12N9/00 , C12N9/2402 , C12Y302/01044
摘要： An isolated gene having a DNA sequence coding for the polypeptide having a degrading activity of the sulfated-fucose-containing polysaccharide or having the functionally identical activity as above.
摘要翻译： 具有编码具有含硫酸化岩藻糖多糖的降解活性或具有与上述功能相同的活性的多肽的DNA序列的分离基因。
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公开(公告)号：EP0870771A4
公开(公告)日：2005-01-19
申请号：EP96910215
申请日：1996-04-22
发明人： SAKAI TAKESHI , KIMURA HITOMI , KOJIMA KAORU , IKAI KATSUSHIGE , AKIYOSHI SUMIKO , NAKANISHI YOSHIKUNI , KATO IKUNOSHIN
IPC分类号： C07H11/00 , C07H1/00 , C07H3/06 , C07H5/10 , C08B37/00 , C12N1/20 , C12N9/24 , C12N9/88 , C12P19/14 , C12P19/44
CPC分类号： C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要： The invention provides a novel endo-type fucoidan hydrolase and a novel microorganism useful for producing sugar compounds. The sugar compounds refer to the compounds represented by general formula (1), wherein at least one alcoholic hydroxyl group has been sulfated, and salts thereof, wherein Y represents hydrogen or a group of general formula (2).
摘要翻译： 一种新型的内切 - 岩藻依聚糖裂解酶和可用于生产糖化合物的新型微生物。 由以下通式（1）表示的糖化合物，其中醇羟基中的至少一个已被硫酸化，或其盐：其中Y表示氢或下式（2）表示的基团。
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公开(公告)号：EP1010761B1
公开(公告)日：2007-12-05
申请号：EP98921819.3
申请日：1998-05-26
申请人： TAKARA BIO INC.
发明人： TAKAYAMA, Masanori, Centr. Research. Laboratories , KOYAMA, Nobuto, Central Research Laboratories , SAKAI, Takeshi, Biomedical Group , KATO, Ikunoshin, Central Research Laboratories
CPC分类号： C12N9/00 , C12N9/2402 , C12Y302/01044
摘要： An isolated gene having a DNA sequence that codes for a polypeptide having the activity of degrading a sulfated fucose-containing polysaccharide or a polypeptide having an activity that is functionally equivalent to that of the above polypeptide.
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5.发明公开ENZYME FOR DECOMPOSITION OF SULFATED FUCAN DERIVED FROM SEA CUCUMBER 审中-公开ENZYM ZUM ABBAU VON AUS SEEGURKE STAMMENDEM SULFATIERTEM FUCAN
公开(公告)号：EP1514923A1
公开(公告)日：2005-03-16
申请号：EP03733522.1
申请日：2003-06-20
申请人： TAKARA BIO INC.
CPC分类号： C12P19/04 , C12N9/16 , C12N9/2402 , C12N9/88 , C12P11/00 , C12Y302/01044 , C12Y302/01051
摘要： Sulfated fucan lyase capable of decomposing sulfated fucan derived from sea cucumber; a process for producing the enzyme; a low molecular compound obtained by causing the enzyme to act on sulfated fucan; a process for producing the same; and an activating factor for sulfated fucan lyase.
摘要翻译： 硫酸化岩藻糖裂解酶能够分解来自海参的硫酸化海藻; 一种生产酶的方法; 通过使酶作用于硫酸化的岩藻糖获得的低分子化合物; 其制造方法; 和硫酸化岩藻糖裂解酶的活化因子。
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公开(公告)号：EP1277834A1
公开(公告)日：2003-01-22
申请号：EP01921895.7
申请日：2001-04-19
申请人： TAKARA BIO INC.
发明人： SAKAI, Takeshi , ISHIZUKA, Kumiko , KOJIMA, Kaoru , SHIMANAKA, Kazuo , IKAI, Katsushige , KATO, Ikunoshin
CPC分类号： C12Y302/01139 , C08B37/00 , C08B37/006 , C12N9/2402 , C12P19/14 , C12R1/01 , C12Y302/01044
摘要： Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
摘要翻译： 三种降解硫酸葡糖醛酸葡聚糖的酶; 生产这些酶的方法; 这些酶的活化剂; 葡糖醛酸葡聚糖硫酸酯及其降解产物; 和一种新型微生物。
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公开(公告)号：EP1010761A4
公开(公告)日：2005-01-05
申请号：EP98921819
申请日：1998-05-26
申请人： TAKARA BIO INC
CPC分类号： C12N9/00 , C12N9/2402 , C12Y302/01044
摘要： An isolated gene having a DNA sequence that codes for a polypeptide having the activity of degrading a sulfated fucose-containing polysaccharide or a polypeptide having an activity that is functionally equivalent to that of the above polypeptide.
摘要翻译： 具有编码具有降解含硫酸化岩藻糖多糖活性的多肽的DNA序列的分离基因或具有与上述多肽功能上等同的活性的多肽。
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公开(公告)号：EP0919237A4
公开(公告)日：2004-10-13
申请号：EP97900470
申请日：1997-01-21
发明人： SAKAI TAKESHI , KITANO HIDEO , YU FU-GONG , NAKAYAMA SHINJI , KOJIMA KAORU , KIMURA HITOMI , NAKANISHI YOSHIKUNI , KATAYAMA KAORU , TOMINAGA TAKANARI , SHIMANAKA KAZUO , IKAI KATSUSHIGE , KATO IKUNOSHIN
IPC分类号： C08B37/00 , A61K31/737 , C12N9/24 , C12P19/04 , C12P19/14 , A61K31/725
CPC分类号： C12Y302/01078 , A61K31/737 , C12N9/2494 , C12P19/14 , C12Y302/01044
摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.
摘要翻译： 含有硫酸化岩藻糖的多糖和/或其降解产物的细胞凋亡诱导剂，抗癌药物和制癌药，以及使用含硫酸化岩藻糖多糖和/或降解产物诱导细胞凋亡的方法 作为活性成分。 一种可用于生产含硫酸化岩藻糖多糖的降解产物的降解酶。
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公开(公告)号：EP1010761A1
公开(公告)日：2000-06-21
申请号：EP98921819.3
申请日：1998-05-26
发明人： TAKAYAMA, Masanori, Centr. Research. Laboratories , KOYAMA, Nobuto, Central Research Laboratories , SAKAI, Takeshi, Biomedical Group , KATO, Ikunoshin, Central Research Laboratories
CPC分类号： C12N9/00 , C12N9/2402 , C12Y302/01044
摘要： An isolated gene having a DNA sequence that codes for a polypeptide having the activity of degrading a sulfated fucose-containing polysaccharide or a polypeptide having an activity that is functionally equivalent to that of the above polypeptide.
摘要翻译： 一种分离的基因，其具有编码具有降解含硫酸化岩藻糖多糖的活性的多肽的DNA序列或具有与上述多肽功能等同的活性的多肽。
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公开(公告)号：EP0870771B1
公开(公告)日：2008-11-12
申请号：EP96910215.1
申请日：1996-04-22
发明人： SAKAI, Takeshi, Res. Inst. for Glycotechnology , KIMURA, Hitomi, Res. Inst. for Glycotechnology , KOJIMA, Kaoru, Res. Inst. for Glycotechnology , IKAI, Katsushige, Takara Shuzo Co., Ltd. , AKIYOSHI, Sumiko, Takara Shuzo Co., Ltd. , NAKANISHI, Yoshikuni, Res.Inst.for Glycotechnology , KATO, Ikunoshin, Res. Inst. for Glycotechnology
CPC分类号： C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要： The invention provides a novel endo-type fucoidan hydrolase and a novel microorganism useful for producing sugar compounds. The sugar compounds refer to the compounds represented by general formula (1), wherein at least one alcoholic hydroxyl group has been sulfated, and salts thereof, wherein Y represents hydrogen or a group of general formula (2).
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