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    BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH
    1.
    发明公开
    BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH 有权
    含苯丁胺盐酸盐的水性贴剂

    公开(公告)号：EP2266553A1

    公开(公告)日：2010-12-29

    申请号：EP09730460.4

    申请日：2009-03-24

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： KAMAKURA, Takashi ,  HOSHIKAWA, Takefumi ,  INAMOTO, Yukiko ,  TANIGAWA, Kayo

    IPC分类号： A61K31/137 ,  A61K9/70 ,  A61K47/10 ,  A61K47/14 ,  A61P31/10

    CPC分类号： A61K31/137 ,  A61K8/0208 ,  A61K8/345 ,  A61K8/37 ,  A61K8/41 ,  A61K8/411 ,  A61K9/7053 ,  A61K9/7061 ,  A61K47/10 ,  A61K47/14 ,  A61Q3/00 ,  A61Q17/005

    摘要： An aqueous patch is provided which has excellent storage stability and provides excellent retention of butenafine hydrochloride blended therein onto the application sites such as skin and nails and is highly therapeutic. The butenafine hydrochloride-containing aqueous patch includes butenafine hydrochloride, glycol salicylate, and propylene glycol in a hydrogel paste. Specifically, the butenafine hydrochloride-containing aqueous patch is produced by dissolving butenafine hydrochloride in a mixed solution of glycol salicylate and propylene glycol and dispersing the resulting solution in a hydrogel is provided. In particular, in the butenafine hydrochloride-containing aqueous patch, glycol salicylate and propylene glycol are mixed in a ratio of 1:2 to 1:30.

    摘要翻译： 提供了一种水性贴剂，其具有优异的储存稳定性，并且在其中掺入的布替萘芬盐酸盐优异地保留在皮肤和指甲等施用部位上，并且是高度治疗性的。 含布替萘芬盐酸盐的水性贴剂包括水凝胶糊剂中的盐酸布替萘芬，水杨酸乙二醇酯和丙二醇。 具体而言，通过将布替萘芬盐酸盐溶解在水杨酸乙二醇酯和丙二醇的混合溶液中并将所得溶液分散在水凝胶中来制备含盐酸布替萘芬水性贴剂。 特别地，在含盐酸布替萘芬的水性贴剂中，水杨酸乙二醇酯和丙二醇以1:2至1:30的比例混合。

    APPARATUS FOR ENVIRONMENTAL SIMULATION MEASUREMENT OF WOUND COATING MATERIAL ON THE SKIN AND MEASUREMENT METHOD THEREFOR
    4.
    发明公开
    APPARATUS FOR ENVIRONMENTAL SIMULATION MEASUREMENT OF WOUND COATING MATERIAL ON THE SKIN AND MEASUREMENT METHOD THEREFOR 审中-公开
    设备用于伤口覆盖材料对皮肤及测量方法环境模拟其测定

    公开(公告)号：EP2246690A1

    公开(公告)日：2010-11-03

    申请号：EP08711766.9

    申请日：2008-02-21

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： TAKAHASHI, Makoto ,  OHURA, Takehiko ,  INAMOTO, Yukiko ,  KAMAKURA, Takashi ,  INAMOTO, Shigeyuki

    IPC分类号： G01N15/08

    CPC分类号： G01N15/08 ,  A61B5/445 ,  A61F2013/00944 ,  A61F2013/00953 ,  G01N5/025 ,  G01N19/04

    摘要： There are provided an apparatus and a method for simulatively measuring an environment in a microspace between a human skin and a wound dressing. The simulative environment-measuring apparatus comprises a constant temperature-and-humidity chamber 14 for controlling an external environment; a heat exchanger 12 disposed in the chamber 14; a constant temperature water bath 10 and a pump 11 for supplying warm water to the heat exchanger; and a container 1 which is set on the heat exchanger 12 and is easily detachable therefrom. The container 1 holds a water retentive member 2 therein, and is covered at its upper opening with a water vapor diffusion-controlling member 4. A microspace 6 formed between the water vapor diffusion-controlling member 4 and a wound dressing 5 placed on the member 4 is a simulatively reproduced space between a human skin and the wound dressing 5. A thin temperature-and-humidity sensor 7 is set in this microspace 6 to measure temperature and humidity with time. When plural containers 1 are used, environments of plural wound dressings 5 can be measured at once.

    摘要翻译： 本发明提供的装置和用于在人类皮肤和伤口敷料之间的微小空间的环境模拟地测量的方法。 所述模拟环境测量装置包括一个恒定的温度和湿度的腔室14对外部环境的控制; 在腔室14设置在热交换器12; 一个恒温水浴10和用于供应热水的热交换器的泵11; 和容器1全部被设置在热交换器12和易于从拆离那里。 容器1保持保水性构件2在其内部，并且被覆盖在其与水蒸汽扩散调整构件4的水蒸汽扩散调整构件4和伤口敷料5之间形成的微小空间6放置在构件上上部开口 图4是人的皮肤和伤口敷料5.一种薄温度和湿度传感器7在该微空间6设置为测量温度和湿度与时间之间的模拟地转载空间。 当多个容器1使用时，多个伤口敷料5的环境可以在一次测量。

    THERAPEUTIC AGENT FOR HEMORRHOIDAL DISEASE
    8.
    发明公开
    THERAPEUTIC AGENT FOR HEMORRHOIDAL DISEASE 审中-公开
    治疗师WIRKSTOFF ZUR BEHANDLUNG VONHÄMORRHOIDALENERKRANKUNGEN

    公开(公告)号：EP1609472A1

    公开(公告)日：2005-12-28

    申请号：EP04711719.7

    申请日：2004-02-17

    申请人： TEIKOKU SEIYAKU CO., LTD.

    发明人： INAMOTO, Yukiko ,  KAWABATA, Seiichiro ,  KAWADA, Mitsuhiro

    IPC分类号： A61K31/616 ,  A61K9/06 ,  A61K9/08 ,  A61K9/70 ,  A61P9/14 ,  A61P43/00

    CPC分类号： A61K31/616 ,  A61K9/0031

    摘要： An external preparation containing acetylsalicylic acid or its pharmaceutically acceptable salt as an active ingredient for treating anal diseases having therapeutic activity on hemorrhoids (internal hemorrhoid, external hemorrhoid), hemorrhoidal disease owing to anal fissure and other anal diseases together with activity on pain and pruritus.

    摘要翻译： 含有乙酰水杨酸或其药学上可接受的盐作为有效成分的外用制剂，用于治疗对痔疮（内痔疮，外痔疮）具有治疗活性的肛门疾病，由肛裂引起的痔疮疾病以及其他肛门疾病以及对疼痛和瘙痒的活动。