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1.发明授权ENZYMATIC TRANSFORMATION OF A PROSTAGLANDIN (BIMATOPROST) INTERMEDIATE 有权前列腺素酶促转化（比马前列素）-ZWISCHENPRODUKTES
公开(公告)号：EP1853719B1
公开(公告)日：2009-09-02
申请号：EP06737313.4
申请日：2006-03-06
CPC分类号： C12P31/00 , C12P41/004
摘要： A method for the selective enzymatic acetylation of a bimatoprost intermediate is provided.
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2.发明公开SELECTIVE ENZYMATIC ESTERIFICATION AND SOLVOLYSIS OF EPIMERIC VITAMIN D ANALOG AND SEPARATION OF THE EPIMERS 有权酶促选择性酯化和溶剂分解差向异构体维生素D类似物和差向异构体分离
公开(公告)号：EP1470220A2
公开(公告)日：2004-10-27
申请号：EP03729607.6
申请日：2003-01-09
IPC分类号： C12N9/20
CPC分类号： C12P7/18 , C12P41/004
摘要： Provided is a method of selectively enzymatically esterifying or selectively enzymatically solvolyzing epimers of analogs of vitamin D having a stereogenic center at C-24 that has a free or esterified OH group. The method can be used, for example, for separating mixed epimers of the vitamin D analog.
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3.发明授权SELECTIVE ENZYMATIC ESTERIFICATION AND SOLVOLYSIS OF EPIMERIC VITAMIN D ANALOG AND SEPARATION OF THE EPIMERS 有权酶促选择性酯化和溶剂分解差向异构体维生素D类似物和差向异构体分离
公开(公告)号：EP1470220B1
公开(公告)日：2011-10-05
申请号：EP03729607.6
申请日：2003-01-09
IPC分类号： C12P41/00
CPC分类号： C12P7/18 , C12P41/004
摘要： Provided is a method of selectively enzymatically esterifying or selectively enzymatically solvolyzing epimers of analogs of vitamin D having a stereogenic center at C-24 that has a free or esterified OH group. The method can be used, for example, for separating mixed epimers of the vitamin D analog.
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4.发明公开ENZYMATIC TRANSFORMATION OF A PROSTAGLANDIN (BIMATOPROST) INTERMEDIATE 有权前列腺素酶促转化（比马前列素）-ZWISCHENPRODUKTES
公开(公告)号：EP1853719A2
公开(公告)日：2007-11-14
申请号：EP06737313.4
申请日：2006-03-06
IPC分类号： C12P41/00
CPC分类号： C12P31/00 , C12P41/004
摘要： A method for the selective enzymatic acetylation of a bimatoprost intermediate is provided.
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