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1.发明授权
公开(公告)号：EP0694068B1
公开(公告)日：2003-02-12
申请号：EP94912200.6
申请日：1994-03-08
IPC分类号： C12N15/12 , C12N15/67 , C12N9/90 , C12N15/10 , C12N5/10 , C12P21/08 , C07K7/06 , C12Q1/68 , G01N33/68 , A61K38/00
CPC分类号： C12N15/1072 , C12N9/90 , C12N15/1079 , C12N15/1082 , C12N15/67 , G01N2800/44
摘要： The invention provides genetic suppressor elements that confer upon a cell resistance to one or more chemotherapeutic drug, methods for identifying and obtaining such elements, and methods of using such elements. The invention also provides cloned genes associated with sensitivity to chemotherapeutic drugs.
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2.发明公开GENES AND GENETIC ELEMENTS ASSOCIATED WITH CONTROL OF NEOPLASTIC TRANSFORMATION IN MAMMALIAN CELLS 失效配施肿瘤性SÄNGETIERZELLEN相关联的控制基因和基因元件
公开(公告)号：EP0749477A1
公开(公告)日：1996-12-27
申请号：EP95912654.0
申请日：1995-03-01
IPC分类号： C12N15 , A61K31 , A61K48 , A61P35 , C07H21 , C07K14 , C12N5 , C12N9 , C12P21 , G01N33 , A61K38 , C12R1
CPC分类号： C12N9/90 , A61K38/00 , C07K14/4703 , C12N15/1034 , C12N15/113 , C12N15/1137 , C12N15/1138 , C12N15/67 , C12N2310/18 , C12N2310/321 , C12Y599/01003 , G01N33/574 , G01N2800/44
摘要： The invention provides genetic suppressor elements that confer the transformed phenotype of malignant mammalian cells upon untransformed cells, methods for identifying and obtaining such elements, methods for isolating and identifying genes corresponding to such elements, and methods of using such elements. The invention also provides genes corresponding to the GSEs of the invention.
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3.发明公开
公开(公告)号：EP0694068A1
公开(公告)日：1996-01-31
申请号：EP94912200.0
申请日：1994-03-08
CPC分类号： C12N15/1072 , C12N9/90 , C12N15/1079 , C12N15/1082 , C12N15/67 , G01N2800/44
摘要： The invention provides genetic suppressor elements that confer upon a cell resistance to one or more chemotherapeutic drug, methods for identifying and obtaining such elements, and methods of using such elements. The invention also provides cloned genes associated with sensitivity to chemotherapeutic drugs.
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