专利检索 ap:("THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES") AND inv:"BUKH, Jens" 第 1 页

1.

发明授权
NUCLEOTIDE AND AMINO ACID SEQUENCES OF THE ENVELOPE 1 AND CORE GENES OF HEPATITIS C VIRUS 无效
标题翻译：丙型肝炎病毒的包膜蛋白1和核心蛋白的基因的核苷酸序列和氨基酸序列

公开(公告)号：EP0779924B1

公开(公告)日：2005-11-09

申请号：EP95930831.3

申请日：1995-08-15

申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

发明人： BUKH, Jens , MILLER, Roger H. , PURCELL, Robert H.

IPC分类号： C12N15/51 , C07K14/18 , G01N33/569 , A61K39/29 , C12Q1/68 , C12Q1/70 , C07K16/10

CPC分类号： C07K14/005 , A61K39/00 , C12N2770/24222 , C12Q1/707 , Y10S435/81

摘要： The nucleotide and deduced amino acid sequences of cDNAs encoding the envelope (1) genes and core genes of isolates of hepatitis C virus (HCV) are disclosed. The invention relates to the oligonucleotides, peptides and recombinant envelope (1) and core proteins derived from these sequences and their use in diagnostic methods and vaccines.

2.

发明授权
CLONED GENOMES OF INFECTIOUS HEPATITIS C VIRUSES AND USES THEREOF 失效
标题翻译：传染性肝炎肝炎病毒基因组克隆及其用途

公开(公告)号：EP0998567B1

公开(公告)日：2008-05-28

申请号：EP98935702.5

申请日：1998-07-16

申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

发明人： YANAGI, Masayuki , BUKH, Jens , EMERSON, Suzanne, U. , PURCELL, Robert, H.

IPC分类号： C12N15/40 , C07K14/18 , C12Q1/70 , C07K16/10 , A61K39/29

CPC分类号： C07K14/005 , A61K39/00 , A61K2039/525 , C07K2319/00 , C12N7/00 , C12N2770/24221 , C12N2770/24222

摘要： The present invention discloses nucleic acid sequences which encode infectious hepatitis C viruses and the use of these sequences, and polypeptides encoded by all or part of these sequences, in the development of vaccines and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV.

3.

发明公开
NUCLEOTIDE AND AMINO ACID SEQUENCES OF THE ENVELOPE 1 AND CORE GENES OF HEPATITIS C VIRUS 无效
标题翻译：丙型肝炎病毒的包膜蛋白1和核心蛋白的基因的核苷酸序列和氨基酸序列

公开(公告)号：EP0779924A2

公开(公告)日：1997-06-25

申请号：EP95930831.0

申请日：1995-08-15

申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

发明人： BUKH, Jens , MILLER, Roger H. , PURCELL, Robert H.

IPC分类号： C07K14 , C12N15 , C12Q1 , A61K39

CPC分类号： C07K14/005 , A61K39/00 , C12N2770/24222 , C12Q1/707 , Y10S435/81

摘要： The nucleotide and deduced amino acid sequences of cDNAs encoding the envelope (1) genes and core genes of isolates of hepatitis C virus (HCV) are disclosed. The invention relates to the oligonucleotides, peptides and recombinant envelope (1) and core proteins derived from these sequences and their use in diagnostic methods and vaccines.