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公开(公告)号：EP3595641A1
公开(公告)日：2020-01-22
申请号：EP18715422.4
申请日：2018-03-16
IPC分类号： A61K9/50 , A61K31/137
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公开(公告)号：EP0989848A2
公开(公告)日：2000-04-05
申请号：EP98921690.8
申请日：1998-06-08
IPC分类号： A61K9/28
CPC分类号： A61K31/663 , A61K9/2081 , A61K9/2866 , A61K31/138 , A61K31/375 , A61K31/401 , A61K31/49 , A61K31/522 , A61K31/65 , A61K31/675 , A61K31/7072 , Y10S514/821 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/963 , Y10S514/964
摘要： A novel oral dosage to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of emepronium bromidebromide, doxycycline, and other tetracyclines/antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine (AZT), bisphosphonates and mixtures thereof and pharmaceutically acceptable excipients, wherein said oral dosage form is a generally oval form and film coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus.
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公开(公告)号：EP3193844A1
公开(公告)日：2017-07-26
申请号：EP15771450.2
申请日：2015-09-18
IPC分类号： A61K9/50 , A61K31/137
CPC分类号： A61K9/5089 , A61K9/5078 , A61K31/137 , B01J2/16
摘要： Forming a coated core by using a fluidized bed processor that discharges a spray containing atomized air and a coating solution where the coating solution contains an active. Then, wetting the core with the coating solution and drying the wetted cores to form coated cores. These steps can be repeated until an appropriate amount of active has been applied. The coated cores are visually perceived as smooth under a microscope with a total magnification of 40X.
摘要翻译： 通过使用流化床处理器形成涂覆的核心，所述流化床处理器释放含有雾化空气的喷雾和涂层溶液含有活性物质的涂层溶液。 然后，用涂层溶液润湿核心并干燥湿核心以形成涂层核心。 这些步骤可以重复进行，直到适用适量的活性物质。 在总放大倍数为40倍的显微镜下，涂层核心在视觉上感觉平滑。
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公开(公告)号：EP0989848B1
公开(公告)日：2004-09-29
申请号：EP98921690.8
申请日：1998-06-08
IPC分类号： A61K9/28
CPC分类号： A61K31/663 , A61K9/2081 , A61K9/2866 , A61K31/138 , A61K31/375 , A61K31/401 , A61K31/49 , A61K31/522 , A61K31/65 , A61K31/675 , A61K31/7072 , Y10S514/821 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/963 , Y10S514/964
摘要： A novel oral dosage to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of emepronium bromidebromide, doxycycline, and other tetracyclines/antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine (AZT), bisphosphonates and mixtures thereof and pharmaceutically acceptable excipients, wherein said oral dosage form is a generally oval form and film coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus.
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公开(公告)号：EP3389625A1
公开(公告)日：2018-10-24
申请号：EP16813272.8
申请日：2016-12-01
IPC分类号： A61K9/00 , A61K31/135
CPC分类号： A61K31/138 , A61J1/03 , A61K9/0053 , A61K9/0056 , A61K9/006 , A61K9/19 , A61K31/135 , A61K31/4425 , A61K47/12 , A61K47/22
摘要： An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeability enhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The diphenhydramine can completely dissolve within about 2 minutes.
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公开(公告)号：EP3193845A1
公开(公告)日：2017-07-26
申请号：EP15771451.0
申请日：2015-09-18
IPC分类号： A61K9/50 , A61K31/137 , A61P11/02
CPC分类号： A61K31/137 , A61K9/1676 , A61K9/5078 , A61K9/5084
摘要： A multi-particle dosage form that can deliver phenylephrine in controlled pulsed doses. The dosage form can contain an immediate release form that can contain phenylephrine or a salt thereof and a plurality of delayed release particles with a coating that can contain phenylephrine or salt thereof and a pH sensitive coating.
摘要翻译： 可以以受控脉冲剂量递送去氧肾上腺素的多颗粒剂型。 剂型可以含有速释形式，其可以含有去氧肾上腺素或其盐以及具有可以含有去氧肾上腺素或其盐和pH敏感性涂层的涂层的多个延迟释放颗粒。
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