PROCESS FOR PREPARING AMIDES OF N-ALKYL POLYHYDROXYALKYL AMINES
    3.
    发明公开
    PROCESS FOR PREPARING AMIDES OF N-ALKYL POLYHYDROXYALKYL AMINES 失效
    制备N-烷基聚羟基烷基胺的酰胺的方法

    公开(公告)号:EP0830339A1

    公开(公告)日:1998-03-25

    申请号:EP96914677.0

    申请日:1996-05-17

    摘要: N-alkyl polyhydroxy alkyl amines such as N-methyl glucamine having a Gardner Color of less than 1 are reacted with sources of fatty acyl groups such as methyl esters, anhydrides, and/or fatty acids that have greater than 98 % transmittance at 460 nm in organic hydroxy solvents such as methanol to prepare N-alkyl polyhydroxy amine amides with good color. The N-alkyl polyhydroxyamines can be purified by crystallization, and/or subjected to reductive bleaching, to provide superior color. The reaction is preferably carried out at low temperature for short periods of time and with low catalyst levels to minimize formation of cyclic products. The resulting amide product can be further purified by treatment with anionic and cationic exchange resins to remove soap and amine impurities. The anionic ion exchange resin can be readily regenerated by acidifying it followed by washing with an organic solvent.

    摘要翻译: N-烷基多羟基烷基胺如加德尔颜色小于1的N-甲基葡糖胺与脂肪酰基基团如甲基酯,酸酐和/或脂肪酸的来源反应,所述脂肪酰基基团在460nm具有大于98%的透光率 在有机羟基溶剂如甲醇中制备具有良好颜色的N-烷基多羟基胺酰胺。 N-烷基多羟基胺可以通过结晶纯化,和/或进行还原漂白以提供优良的颜色。 该反应优选在低温下短时间和低催化剂水平进行以使环状产物的形成最小化。 所得到的酰胺产物可以通过用阴离子和阳离子交换树脂处理进一步纯化以除去肥皂和胺杂质。 阴离子交换树脂可以通过酸化而容易地再生,然后用有机溶剂洗涤。