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公开(公告)号：EP2861217B1
公开(公告)日：2017-09-06
申请号：EP13804554.7
申请日：2013-06-13
CPC分类号： A61K9/107 , A61K9/1075 , A61K38/00 , A61K39/39 , A61K47/48561 , A61K47/488 , A61K47/6849 , A61K47/6907 , A61K2039/55516 , A61K2039/55566 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/001 , C07K16/2851 , C07K2319/33
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公开(公告)号：EP3046870A1
公开(公告)日：2016-07-27
申请号：EP14843901.1
申请日：2014-09-16
CPC分类号： B01J13/06 , A01N25/28 , A01N25/30 , A01N43/56 , A61K9/1075 , A61K9/501 , A61K9/5031 , A61K9/5052 , A61K9/5115 , A61K9/5123 , A61K9/5146 , A61K9/5169 , A61K38/16 , B01F17/005 , B82Y5/00 , C07K7/06 , C07K14/00 , C07K14/001
摘要： The present invention relates to emulsion-templated silica micro and nano-capsules- and methods for making them. In particular, the template emulsion is stabilized by a biosurfactant that also assists in nucleating the silica shell Mineralizing biosurfactants and stabilized micro- and nano-emulsions useful in forming the emulsion-templated micro- and nano-capsules, and methods for the use of the silica micro- and nano-capsules are also described.
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公开(公告)号：EP1858914A1
公开(公告)日：2007-11-28
申请号：EP06704911.4
申请日：2006-02-24
CPC分类号： C07K14/00 , B01D17/047 , C07K1/00 , C07K1/107 , C07K7/06 , C07K14/001 , C07K14/47
摘要： Methods of modulating interfacial characteristics in a self-assembled, force-transmitting peptide network at a fluid-fluid interface are disclosed. The methods involve exposing a peptide capable of participating in a self-assembled, force-transmitting peptide network, either before or after it interacts with other peptides to form the peptide network to a stimulus that alters the chemical and/or physical properties of the peptide. Use of such methods in applications such as emulsions and foams are also disclosed.
摘要翻译： 公开了在流体 - 流体界面处调节自组装，力传递肽网络中的界面特征的方法。 该方法包括在能够参与自组装的力传递肽网络的肽之前或之后，将其与其他肽相互作用以形成肽网络以形成改变肽的化学和/或物理性质的刺激物 。 也公开了在诸如乳液和泡沫的应用中使用这些方法。
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公开(公告)号：EP2742139A1
公开(公告)日：2014-06-18
申请号：EP12822010.0
申请日：2012-08-13
IPC分类号： C12N15/62 , A61K39/09 , A61K39/145 , A61K39/21 , A61K39/155 , A61P31/22
CPC分类号： C07K14/315 , A61K9/1075 , A61K9/5184 , A61K39/09 , A61K39/092 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/21 , A61K2039/523 , A61K2039/5256 , A61K2039/5258 , A61K2039/55505 , A61K2039/55555 , A61K2039/55566 , C07K14/005 , C12N15/62 , C12N2710/22022 , C12N2710/22043 , C12N2760/16134 , C12N2760/18234 , Y02A50/467
摘要： The present invention provides compositions relating to viral capsomeres which comprise foreign immunogenic sequences for use in pharmaceutical compositions and methods of producing such compositions, and related isolated or purified protein and nucleic acid molecules, vectors, host cells, compositions, and methods of use to augment an immune response, immunize an animal and prophylactically or therapeutically treat a disease, disorder or condition. The viral capsomere may be derived from a polyomavirus and comprise an immunogen of interest at the N-terminus and further at the C-terminus and/or at one or more exposed loops of the capsomere.
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公开(公告)号：EP1858914B1
公开(公告)日：2013-12-04
申请号：EP06704911.4
申请日：2006-02-24
CPC分类号： C07K14/00 , B01D17/047 , C07K1/00 , C07K1/107 , C07K7/06 , C07K14/001 , C07K14/47
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公开(公告)号：EP2861217A1
公开(公告)日：2015-04-22
申请号：EP13804554.7
申请日：2013-06-13
CPC分类号： A61K9/107 , A61K9/1075 , A61K38/00 , A61K39/39 , A61K47/48561 , A61K47/488 , A61K47/6849 , A61K47/6907 , A61K2039/55516 , A61K2039/55566 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/001 , C07K16/2851 , C07K2319/33
摘要： The invention relates to nanoemulsions useful for analytical techniques and delivery of cargoes such as pharmaceutically active agents. In particular, the invention relates to nanoemulsions comprising an oil phase dispersed in an aqueous phase and at least two peptide surfactants adsorbed at the liquid-liquid interface, one peptide surfactant comprising a short peptide sequence having α-helical propensity and at least one second polypeptide surfactant comprising at least two peptide sequences having α-helical propensity linked by a linking sequence of 3 to 11 amino acid residues. Optionally the at least one second polypeptide surfactant comprises at least one pharmacokinetic modifying agent and/or a targeting agent. Furthermore, the nanoemulsion may further comprise a cargo such as a pharmaceutically active agent.
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