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1.发明授权
公开(公告)号：EP1789593B1
公开(公告)日：2017-03-15
申请号：EP05857509.3
申请日：2005-07-07
IPC分类号： C07K14/005
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/155 , A61K2039/505 , A61K2039/575 , A61K2039/6075 , C07K14/07 , C07K14/115 , C07K16/1027 , C07K2319/40 , C12N7/00 , C12N2710/24141 , C12N2760/18222 , C12N2760/18234 , C12N2760/18271 , G01N33/56983 , G01N33/6854
摘要： This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
摘要翻译： 本发明涉及来自Hendra和Nipah病毒的G糖蛋白的可溶形式。 特别地，本发明涉及包含来自Hendra和Nipah病毒的G糖蛋白的可溶形式的组合物，还涉及使用Hendra和Nipah病毒的G糖蛋白的可溶形式的诊断和治疗方法。 此外，本发明涉及包括中和抗体的治疗性抗体和用于预防和治疗Hendra和Nipah病毒感染的疫苗。
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公开(公告)号：EP2707025A4
公开(公告)日：2014-12-17
申请号：EP12785009
申请日：2012-05-14
发明人： ELHAY MARTIN , BRODER CHRISTOPHER C , HUANG JIN-AN
IPC分类号： A61K39/155
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/54 , A61K2039/544 , A61K2039/545 , A61K2039/55505 , A61K2039/55511 , A61K2039/55561 , A61K2039/55577 , C07K14/005 , C12N7/00 , C12N2710/24143 , C12N2760/18222 , C12N2760/18234 , G01N33/56983 , G01N2333/115 , G01N2469/20
摘要： Immunogenic compositions directed against Hendra and/or Nipah viruses, and methods of its use, are provided. In addition, methods of distinguishing subjects vaccinated with the immunogenic compositions of the invention from those infected with Hendra and/or Nipah virus are provided.
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公开(公告)号：EP2495252A2
公开(公告)日：2012-09-05
申请号：EP12157071.7
申请日：2005-07-07
IPC分类号： C07K14/115 , A61K39/155 , C12N15/62
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/155 , A61K2039/505 , A61K2039/575 , A61K2039/6075 , C07K14/07 , C07K14/115 , C07K16/1027 , C07K2319/40 , C12N7/00 , C12N2710/24141 , C12N2760/18222 , C12N2760/18234 , C12N2760/18271 , G01N33/56983 , G01N33/6854
摘要： This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
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公开(公告)号：EP1789593A2
公开(公告)日：2007-05-30
申请号：EP05857509.3
申请日：2005-07-07
IPC分类号： C12Q1/70
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/155 , A61K2039/505 , A61K2039/575 , A61K2039/6075 , C07K14/07 , C07K14/115 , C07K16/1027 , C07K2319/40 , C12N7/00 , C12N2710/24141 , C12N2760/18222 , C12N2760/18234 , C12N2760/18271 , G01N33/56983 , G01N33/6854
摘要： This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
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公开(公告)号：EP3082856A1
公开(公告)日：2016-10-26
申请号：EP14830912.3
申请日：2014-12-15
申请人： Zoetis Services LLC
发明人： EDWARDS, Nigel , HUANG, Jinan , WAREING, Mark
IPC分类号： A61K39/155
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/525 , A61K2039/545 , A61K2039/552 , A61K2039/55577 , A61K2039/575 , C12N7/00 , C12N2760/18022 , C12N2760/18034 , C12N2760/18071 , C12N2760/18222 , C12N2760/18234 , C12N2760/18271
摘要： This invention relates to Hendra and Nipah immunogenic compositions and methods of use. The invention also relates to methods of distinguishing subjects vaccinated with the immunogenic compositions of the invention from those infected with Hendra and/or Nipah virus.
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6.发明公开
公开(公告)号：EP2844746A4
公开(公告)日：2016-07-20
申请号：EP13769106
申请日：2013-03-15
申请人： UNIV CALIFORNIA
发明人： LEE BENHUR , PALOMARES KARINA , PERNET OLIVIER
CPC分类号： A61K48/0008 , A61K39/12 , A61K48/00 , A61K48/0075 , C12N7/00 , C12N15/86 , C12N2740/15021 , C12N2740/15032 , C12N2740/15041 , C12N2740/15043 , C12N2740/15071 , C12N2760/18222 , C12N2760/18232 , C12N2760/18234 , C12N2760/18241 , C12N2760/18245 , C12N2760/18271 , C12N2810/6027 , C12N2810/6072
摘要： The present invention relates to lentiviral particles which have been pseudotyped with Nipah virus (NiV) fusion (F) and attachment (G) glycoproteins (NiVpp-F/G). Additionally, the present invention relates to truncated NiV-F glycoproteins useful in producing such NiVpp lentiviral particles, as well as to additional variant peptides which enhance activity. Further, the present invention relates to methods of using such lentiviral particles or sequences, for example in the treatment of cancer or CNS disorders.
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公开(公告)号：EP2866829A4
公开(公告)日：2015-12-09
申请号：EP13813542
申请日：2013-07-02
申请人： JACKSON H M FOUND MILITARY MED , COMMW SCIENT IND RES ORG , STATE OF QUEENSLAND ACTING THROUGH THE DEPT OF AGRICULTURE FISHERIES AND FORESTRY
发明人： WANG LINFA , MARSH GLENN A , FIELD HUME , BRODER CHRISTOPHER
IPC分类号： A61K39/155 , A61K48/00 , C12N15/00 , C12Q1/68
CPC分类号： C12Q1/701 , A61K39/00 , A61K39/12 , A61K2039/543 , C07K14/005 , C07K16/1027 , C07K2317/76 , C12N7/00 , C12N2760/18221 , C12N2760/18222 , C12N2760/18231 , C12N2760/18234 , C12Q2600/136
摘要： The present invention is directed towards a novel virus, called Cedar Virus, and its methods of use.
摘要翻译： 本发明涉及称为雪松病毒的新型病毒及其使用方法。
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8.发明公开
公开(公告)号：EP2714722A1
公开(公告)日：2014-04-09
申请号：EP12725974.5
申请日：2012-05-23
申请人： Merial Limited
IPC分类号： C07K14/115 , A61K39/155
CPC分类号： A61K39/155 , A61K39/12 , A61K2039/505 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2710/24043 , C12N2760/18222 , C12N2760/18234 , C12N2799/023
摘要： The present invention provides vectors that contain and express in vivo or in vitro one or more Hendra virus polypeptides or antigens that elicit an immune response in animal or human against Hendra virus and Nipah virus, compositions comprising said vectors and/or Hendra virus polypeptides, methods of vaccination against Hendra virus and Nipah virus, and kits for use with such methods and compositions.
摘要翻译： 本发明提供了在体内或体外含有一种或多种Hendra病毒多肽或在动物或人体中引起针对亨德拉病毒和尼帕病毒的免疫应答的抗原的载体，包含所述载体和/或亨德拉病毒多肽的组合物，方法 针对亨德拉病毒和尼帕病毒接种疫苗，以及用于此类方法和组合物的试剂盒。
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公开(公告)号：EP1881845B1
公开(公告)日：2010-03-24
申请号：EP06750224.5
申请日：2006-04-14
申请人： Merial Ltd.
IPC分类号： A61K39/155
CPC分类号： C07K14/005 , A61K39/12 , A61K39/155 , A61K2039/5254 , A61K2039/5256 , A61K2039/70 , C12N15/86 , C12N2710/24043 , C12N2760/18222 , C12N2760/18234
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公开(公告)号：EP3381930A1
公开(公告)日：2018-10-03
申请号：EP18160722.7
申请日：2005-07-07
IPC分类号： C07K14/005 , A61K39/00 , A61K38/00 , A61K39/12
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/155 , A61K2039/505 , A61K2039/575 , A61K2039/6075 , C07K14/07 , C07K14/115 , C07K16/1027 , C07K2319/40 , C12N7/00 , C12N2710/24141 , C12N2760/18222 , C12N2760/18234 , C12N2760/18271 , G01N33/56983 , G01N33/6854
摘要： This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
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