专利检索 ap:("TRANSKARYOTIC THERAPIES, INC.") AND inv:"SCHMIDT, Bernhard" 第 1 页

1.

发明公开
DIAGNOSIS AND TREATMENT OF MULTIPLE SULFATASE DEFICIENCY AND OTHER USING A FORMYLGLYCINE GENERATING ENZYME (FGE) 有权
标题翻译：诊断和多种硫酸疾病治疗和另一个使用一个甲酰酶LOWER

公开(公告)号：EP1592786A2

公开(公告)日：2005-11-09

申请号：EP04709824.9

申请日：2004-02-10

申请人： TRANSKARYOTIC THERAPIES, INC.

发明人： VON FIGURA, Kurt , SCHMIDT, Bernhard , DIERKS, Thomas , HEARTLEIN, Michael, W. , BALLABIO, Andrea , COSMA, Maria, Pia

IPC分类号： C12N9/02 , C12N15/52 , C12Q1/68 , A61K38/44 , A61K31/7088 , G01N33/68

CPC分类号： A61K48/0066 , A61K38/00 , A61K38/44 , A61K38/465 , A61K2039/53 , C12N9/0051 , C12N9/0071 , C12N9/16 , C12Y108/99 , C12Y301/06013 , Y02A50/473

摘要： This invention relates to methods and compositions for the diagnosis and treatment of Multiple Sulfatase Deficiency (MSD) as well as other sulfatase deficiencies. More specifically, the invention relates to isolated molecules that modulate post-translational modifications on sulfatases. Such modifications are essential for proper sulfatase function.

摘要翻译： 本发明涉及一种用于多硫酸酯酶缺乏症（MSD）以及其它硫酸酯酶缺乏症的诊断和治疗方法和组合物。更具体地，本发明涉及分离的分子做调节硫酸酯酶上翻译后修饰。搜索修改是正常硫酸酯酶功能所必需的。