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公开(公告)号：EP3784226A1
公开(公告)日：2021-03-03
申请号：EP19791620.8
申请日：2019-04-24
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： A61K31/166 , C07C233/65
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公开(公告)号：EP3718569A1
公开(公告)日：2020-10-07
申请号：EP20159132.8
申请日：2016-05-23
发明人： WANG, Tong , GATELY, Stephen , GONZALES, Paul
IPC分类号： A61K39/395 , C07K16/28 , A61K31/4184 , C07D235/30 , C07D401/04 , C07D403/04 , A61P35/00 , A61P35/04
摘要： The present invention describes a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.
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公开(公告)号：EP3297674A1
公开(公告)日：2018-03-28
申请号：EP16800623.7
申请日：2016-05-23
发明人： WANG, Tong , GATELY, Stephen , GONZALES, Paul
IPC分类号： A61K39/395 , A61K31/4184 , C07D235/30 , C07D401/04 , C07D403/04
CPC分类号： A61K39/3955 , A61K31/4184 , A61K31/7068 , A61K45/06 , A61K47/18 , A61K47/22 , A61K47/26 , A61K2039/507 , A61K2300/00 , A61P35/00 , C07D235/30 , C07D401/04 , C07D403/04 , C07K16/2818 , C07K2317/76
摘要： The present invention describes compositions, including pharmaceutical compositions, comprising a PD-1 axis binding antagonist, a CTLA4 antagonist, or a DNA demethylating agent and a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.
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公开(公告)号：EP3297437A1
公开(公告)日：2018-03-28
申请号：EP16797227.2
申请日：2016-05-18
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： A01N43/40
CPC分类号： C07D495/04 , A61K31/4184 , A61K31/4353 , A61K31/4465 , A61K31/506 , A61K45/06 , C07D401/04 , C07D403/04 , A61K2300/00
摘要： The present invention is directed to certain amides and heterocyclic compounds. The present invention also relates to uses of these compounds to treat several diseases including autoimmune disorders, cardiovascular disorders, inflammation, central nervous system disorders, arterial thrombotic disorders, fibrotic disorders, glaucoma, and neoplastic disorders.
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5.发明公开
公开(公告)号：EP3679019A1
公开(公告)日：2020-07-15
申请号：EP18853881.3
申请日：2018-09-06
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： C07D235/30 , C07D401/04 , C07D403/04
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公开(公告)号：EP4209228A1
公开(公告)日：2023-07-12
申请号：EP22212373.9
申请日：2016-05-23
发明人： WANG, Tong , GATELY, Stephen , GONZALES, Paul
IPC分类号： A61K39/395 , C07K16/28 , A61K31/4184 , C07D235/30 , C07D401/04 , C07D403/04 , A61P35/00 , A61P35/04
摘要： The present invention describes a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.
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公开(公告)号：EP3893863A1
公开(公告)日：2021-10-20
申请号：EP19897354.7
申请日：2019-12-09
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： A61K31/16 , A61K31/426 , C07C233/30
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公开(公告)号：EP3544601A1
公开(公告)日：2019-10-02
申请号：EP17875035.2
申请日：2017-11-24
发明人： WANG, Tong , GATELY, Stephen , GONZALES, Paul
IPC分类号： A61K31/166 , A61K31/4164 , A61K31/4184 , C07C259/10 , C07D235/30
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公开(公告)号：EP3532479A1
公开(公告)日：2019-09-04
申请号：EP17863621.3
申请日：2017-10-24
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： C07D493/10 , C07D495/04 , A61K31/5377
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公开(公告)号：EP3423439A1
公开(公告)日：2019-01-09
申请号：EP16892907.3
申请日：2016-05-23
发明人： WANG, Tong , GATELY, Stephen
IPC分类号： C07D235/30 , C07D401/04 , C07D403/04
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