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1.发明公开METHODS AND APPARATUS FOR TRANSMYOCARDIAL DIRECT CORONARY REVASCULARIZATION 失效方法和设备直接transmyocardial冠状动脉血运重建
公开(公告)号：EP0981295A4
公开(公告)日：2005-02-02
申请号：EP98915524
申请日：1998-04-13
申请人： TRANSVASCULAR INC
发明人： MAKOWER JOSHUA , FLAHERTY J CHRISTOPHER , MACHOLD TIMOTHY R , WHITT JASON BRIAN , TUMAS MARGARET W , LAMSON THEODORE C , JENSEN MARC
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/12 , A61B17/30 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/24 , A61F2/90 , A61F2/94 , A61L27/00 , A61M25/00 , A61M39/24 , A61F2/06 , A61F2/14 , A61M1/12 , A61M29/02
CPC分类号： A61B17/00234 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12131 , A61B17/12136 , A61B17/12172 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/07 , A61F2/2412 , A61F2/2418 , A61F2/2421 , A61F2/2475 , A61F2/2493 , A61F2/90 , A61F2/94 , A61F2002/30079 , A61F2210/009 , A61F2220/0008 , A61M39/24 , A61M2025/0076 , A61M2025/1052
摘要： Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vesel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.
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2.发明公开DEVICES FOR FORMING AND/OR MAINTAINING CONNECTIONS BETWEEN ADJACENT ANATOMICAL CONDUITS 审中-公开创建设备和/或从获得之间的相邻解剖线的连接
公开(公告)号：EP1037571A4
公开(公告)日：2003-05-28
申请号：EP98957744
申请日：1998-11-10
申请人： TRANSVASCULAR INC
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/12 , A61B17/30 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/06 , A61F2/82 , A61F2/90 , A61M25/00 , A61M25/095
CPC分类号： A61F2/91 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/064 , A61F2/07 , A61F2/2493 , A61F2/90 , A61F2/915 , A61F2002/061 , A61F2002/30079 , A61F2002/825 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2210/009 , A61F2230/0054 , A61F2250/0048 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： Implantable connector devices (10) which are useable to maintain fluidic connection between or approximation of, openings formed in adjacent natural or prosthetic anatomical conduits (or adjacent openings formed in a single anatomical conduit). These connector devices (10) generally comprise a plurality of radially expandable annular members (12a-12c) having one or more elongate strut members (14) extending therebetween. Initially, the device (10) is mountable on or within a delivery catheter while in a radially compact configuration. After the delivery catheter has been inserted into the body, the device is caused to transition to a radially expanded configuration whereby it becomes implanted within the body so as to maintain the desired fluidic connection between, or the desired approximation of, the anatomical conduit(s).
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3.发明公开TRANSLUMINAL DEVICES, SYSTEMS AND METHODS FOR ENLARGING INTERSTITIAL PENETRATION TRACTS 审中-公开腔内装置，系统和扩大间质性穿透ROUTES方法
公开(公告)号：EP1069869A4
公开(公告)日：2006-03-08
申请号：EP99916412
申请日：1999-04-06
申请人： TRANSVASCULAR INC
IPC分类号： A61B18/20 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/14 , A61B18/22 , A61B18/24 , A61B19/00 , A61M29/02 , A61D17/00
CPC分类号： A61B17/32075 , A61B17/32002 , A61B18/1482 , A61B18/245 , A61B2017/00252 , A61B2017/22069 , A61B2018/2255 , A61B2018/2266 , A61B2018/2272 , A61B2090/036 , A61B2090/065 , A61M25/104
摘要： This invention is methods, apparatus, and systems for enlarging interstitial penetration tracts which have been formed between blood vessels or elsewhere within the body of a mammalian patient. Included are de-bulking type tract enlarging systems (10, 10a), dilation-type tract enlarging systems (10b), tissue-sclicing-type tract enlarging systems (10c), and two-catheter-type tract enlarging systems (17).
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4.发明公开TISSUE PENETRATING CATHETHERS HAVING INTEGRAL IMAGING TRANSDUCERS AND THEIR METHODS OF USE 有权面料采取紧急留置针于成像转换器及相关应用方法
公开(公告)号：EP1067869A4
公开(公告)日：2002-08-21
申请号：EP99916238
申请日：1999-03-31
申请人： TRANSVASCULAR INC
IPC分类号： A61B8/12 , A61B17/00 , A61B17/11 , A61B17/22 , A61B17/32 , A61B17/34 , A61B19/00 , A61M25/00 , A61M25/01
CPC分类号： A61M25/0108 , A61B17/22 , A61B17/3207 , A61B2017/00252 , A61B2017/00455 , A61B2017/22077 , A61B2090/3784 , A61B2090/3925
摘要： A catheter device (11) that is useable to penetrate from a blood vessel in which the catheter device (11) is positioned to a target location, comprises a flexible catheter advanced into the blood vessel, a tissue penetrator (85) which is useable to penetrate from the blood vessel to the target location when properly aimed. Further said catheter includes an imaging transducer (81) fixedly mounted on or within the catheter body (13) to provide an imaging signal from which an image of the target location can be obtained. The catheter device (11) may include an imaged marker (101) on the catheter to form on the image obtainable from the imaging signal a penetrator path indication that indicates the path that will be followed by the tissue penetrator when the tissue penetrator (85) exits from the catheter (11). Alternatively, or in addition thereto, the imaging transducer (81) may comprise a plurality of imaging elements.
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5.发明公开DEVICES AND METHODS FOR TRANSLUMINAL OR TRANSTHORACIC INTERSTITIAL ELECTRODE PLACEMENT 有权装置和方法腔内或TEE INTERSTITIAL电极放置
公开(公告)号：EP1496956A4
公开(公告)日：2006-03-22
申请号：EP03719721
申请日：2003-04-11
申请人： TRANSVASCULAR INC
IPC分类号： A61N1/05 , A61B19/00 , A61M20060101 , A61M1/00 , A61N1/362
CPC分类号： A61N1/0573 , A61B2017/22095 , A61N1/056 , A61N1/0587 , A61N2001/0578 , A61N2001/0585
摘要： Methods and devices for implanting pacing electrodes or other apparatus, or for delivering substances, to the heart of other tissues within the body. A guided tissue penetrating catheter is inserted into a body lumen (e.g., blood vessel) or into a body cavity or space (e.g., the pericardial space) and a penetrator is advanced from the catheter to a target location. In some embodiments, a substance or an apparatus (such as an electrode) may be delivered through a lumen in the penetrator. In other embodiments, a guidewire may be advanced through the penetrator, the penetrating catheter may then be removed and an apparatus (e.g., electrode) may then be advanced over that guidewire. Also disclosed are various implantable electrodes and electrode anchoring apparatus.
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6.发明公开CATHETERS, SYSTEMS AND METHODS FOR PERCUTANEOUS IN SITU ARTERIO-VENOUS BYPASS 有权导管系统和经皮静脉INSITU BYPASS方法
公开(公告)号：EP1067874A4
公开(公告)日：2005-12-07
申请号：EP99917329
申请日：1999-03-31
申请人： TRANSVASCULAR INC
发明人： FLAHERTY J CHRISTOPHER , WHITT JASON B , MACAULAY PATRICK E , THOLFSEN DAVID R , GARIBOTTO JOHN T , EVARD PHILLIP C
IPC分类号： A61B8/12 , A61B17/00 , A61B17/11 , A61B17/22 , A61B17/32 , A61B17/34 , A61B19/00 , A61M25/00 , A61M25/01
CPC分类号： A61M25/0108 , A61B17/22 , A61B17/3207 , A61B2017/00252 , A61B2017/00455 , A61B2017/22077 , A61B2090/3784 , A61B2090/3925
摘要： A system of catheter devices (10), and methods for forming channels or passageways between a luminal anatomical structure (e.g., a blood vessel), a target location (e.g., another blood vessel, an organ, a mass of tissue, etc.) for the purpose of rerouting blood flow or for delivering a substance or instrument, etc. to the target location.
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7.发明公开CATHETERS AND RELATED DEVICES FOR FORMING PASSAGEWAYS BETWEEN BLOOD VESSELS OR OTHER ANATOMICAL STRUCTURES 失效导管和亲戚设备对于地层之间BLUTBAHNEN和其他解剖组织渠道
公开(公告)号：EP0964636A4
公开(公告)日：2004-07-21
申请号：EP98920833
申请日：1998-04-10
申请人： TRANSVASCULAR INC , MAKOWER JOSHUA
发明人： MAKOWER JOSHUA , FLAHERTY J CHRISTOPHER , MACHOLD TIMOTHY R , WHITT JASON BRIAN , EVARD PHILIP CHRISTOPHER , MACAULAY PATRICK EDWARD , GARIBOTTO JOHN THOMAS , TUMAS MARGARET W , SELFRIDGE ALAN ROBERT
IPC分类号： A61B17/32 , A61B1/00 , A61B1/04 , A61B8/12 , A61B17/00 , A61B17/064 , A61B17/11 , A61B17/12 , A61B17/22 , A61B17/30 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/00 , A61F2/02 , A61M25/00 , A61M25/01 , A61M25/095 , A61M29/00 , A61B1/06 , A61B1/12 , A61B5/00 , A61B5/04 , A61B8/00 , A61B17/20 , A61M25/06 , A61B17/36
CPC分类号： A61B17/3439 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/3207 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22067 , A61B2017/22068 , A61B2017/22069 , A61B2017/22072 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61B2090/0811 , A61B2090/378 , A61B2090/3925 , A61B2090/3929 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M25/0084 , A61M25/0141 , A61M25/0147 , A61M25/0155 , A61M29/00 , A61M29/02 , A61M2025/0076 , A61M2025/009 , A61M2025/1052
摘要： The inventions described in this patent application include i) a torqueable introducer sheath which is useable in conjunction with a transvascular passageway forming catheter to effect precise rotational control of the catheter; ii) an anchorable guide catheter which is useable in conjunction with an intravascular imaging catheter and a transvascular passageway-forming catheter to effect precise positioning and aiming of the passageway-forming catheter; iii) a passageway forming catheter having a torqueable proximal portion to facilitate precise rotational positioning of the distal portion of the catheter; iv) a deflectable-tipped passageway forming catheter, v) various markers and other apparatus useable in conjunction with any of the passageway-forming catheters to facilitate precise positioning and aiming of the catheter, and vi) an apparatus which may be formed within a catheter to prevent a member, apparatus of flow of material from being inadvertently advanced through a lumen of the catheter.
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8.发明公开SYSTEMS AND METHODS FOR DELIVERING DRUGS TO SELECTED LOCATIONS WITHIN THE BODY 审中-公开系统和给药方法药物对选定的身体SET
公开(公告)号：EP1066070A4
公开(公告)日：2009-08-05
申请号：EP99909978
申请日：1999-03-17
申请人： TRANSVASCULAR INC
发明人： FLAHERTY J CHRISTOPHER , MAKOWER JOSHUA , EVARD PHILIP C , MACAULAY PATRICK E , WHITT JASON B , COLLOTON ROBERT C , MACFARLANE K ANGELA
IPC分类号： A61B8/12 , A61B17/00 , A61B17/064 , A61B17/11 , A61B17/12 , A61B17/22 , A61B17/30 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/00 , A61F2/02 , A61F2/958 , A61M25/00 , A61M25/095 , A61M39/02 , A61M39/04 , A61M5/00 , A61M5/178
CPC分类号： A61M25/0084 , A61B8/12 , A61B17/00491 , A61B17/0643 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/22 , A61B17/3417 , A61B18/00 , A61B18/1477 , A61B18/1492 , A61B90/40 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00504 , A61B2017/1107 , A61B2017/1139 , A61B2017/12127 , A61B2017/22077 , A61B2017/306 , A61B2017/347 , A61B2018/00392 , A61B2018/1425 , A61F2/2493 , A61F2002/30079 , A61F2210/009 , A61M5/007 , A61M5/46 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0108 , A61M39/0208 , A61M39/04 , A61M2025/0037 , A61M2025/0076 , A61M2025/0086 , A61M2025/0087 , A61M2025/009 , A61M2025/0096 , A61M2025/1052
摘要： A trans-vascular system (10) for delivering a drug to a tissue region from a blood vessel, such as a coronary vein, includes a catheter (12) having a distal portion (26) with puncturing (14), orientation (16), drug delivery (62), and imaging elements (18). The puncturing element (14) is deployed for penetrating the vessel wall to access the tissue region. The orientation element (16), e.g., a 'cage' including a plurality of struts (38, 40), and/or a radiopaque marker has a predetermined relationship with the location of the orientation element (16) with respect to the tissue region to orient the puncturing element (14). The catheter (12) is percutaneously introducing into the vessel, the puncturing element (14) is oriented towards the tissue region, the puncturing element (14) is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device (230) may also be deployed to create a cavity in the tissue region for receiving the drug therein, or an indwelling catheter (214) may be advanced into, and left in the tissue region. An implanted reservoir device (350) is also disclosed, including an enclosed membrane (354) on an expandable frame (352) that defines a reservoir, and includes a porous region. The reservoir device may be deployed, expanded within a blood vessel, and may be filled in situ or pre-filled with a drug that passes through the porous region. Alternatively, a pair of expandable endovascular blockers may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.
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9.发明公开DEVICES, SYSTEMS AND METHODS FOR ACUTE OR CHRONIC DELIVERY OF SUBSTANCES OR APPARATUS TO EXTRAVASCULAR TREATMENT SITES 有权设备，系统和方法急性或物质或装置的加分血管治疗慢性分布
公开(公告)号：EP1359967A4
公开(公告)日：2005-10-12
申请号：EP02718838
申请日：2002-01-17
申请人： TRANSVASCULAR INC
发明人： MAKOWER JOSHUA , LAMSON THEODORE C , FLAHERTY J CHRISTOPHER , REGGIE JOHN A , CHANG JOHN Y , CANTANESE III JOSEPH , THOLFSEN DAVID R
IPC分类号： A61M31/00 , A61B17/00 , A61B17/12 , A61B18/24 , A61M5/14 , A61M25/00 , A61M25/01 , A61M25/06
CPC分类号： A61M25/065 , A61B17/00491 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12136 , A61B17/12186 , A61B18/24 , A61B2017/00243 , A61B2017/00247 , A61B2017/00575 , A61B2018/00392 , A61M25/0069 , A61M25/0084 , A61M25/0102 , A61M2025/018
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