公开(公告)号：EP0582796A1

公开(公告)日：1994-02-16

申请号：EP93108651.6

申请日：1993-05-28

申请人： Takeda Chemical Industries, Ltd.

发明人： Shintani, Asae ,  Sasada, Reiko ,  Igarashi, Koichi

IPC分类号： C12N15/85 ,  C07K14/48 ,  C12N5/10 ,  C12N15/12

CPC分类号： C12N15/85 ,  A61K38/00 ,  C07K14/475 ,  C12N2830/008 ,  C12N2830/85

摘要： A novel DNA isolate encoding for a promoter region of human nerve growth factor-2, a recombinant vector containing said DNA, and a transformant carrying said recombinant vector are disclosed. The promoter of the present invention is useful as a means for analyzing an expression control mechanism of a nerve specific protein and can be used as a promoter which is incorporated into vectors used in the preparation of disease model animals, the treatment of diseases of organisms and the establishment of drug screening systems.

摘要翻译： 公开了编码人神经生长因子-2的启动子区域的新型DNA分离物，含有所述DNA的重组载体和携带所述重组载体的转化体。 本发明的启动子可用作分析神经特异性蛋白质的表达控制机制的手段，并且可用作引入到用于制备疾病模型动物的载体中的启动子，生物体疾病的治疗和 建立药物筛查系统。