专利检索 ap:("Technische Universität Braunschweig" OR "Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.") AND inv:"GRUENEFELD, Johann" 第 1 页

1.

发明授权
NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME 有权

公开(公告)号：EP3319940B1

公开(公告)日：2019-05-29

申请号：EP15736269.0

申请日：2015-07-10

申请人： Technische Universität Braunschweig , Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： KUNICK, Conrad , LANDE, Hoang , GRUENEFELD, Johann , DZIKOWSKI, Ron , NASEREDDIN, Abed

IPC分类号： C07D209/12

2.

发明公开
NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME 审中-公开
标题翻译：具有抗原活性的新吲哚化合物及其用途以及生产相同物质的方法

公开(公告)号：EP3319940A1

公开(公告)日：2018-05-16

申请号：EP15736269.0

申请日：2015-07-10

申请人： Technische Universität Braunschweig , Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： KUNICK, Conrad , LANDE, Hoang , GRUENEFELD, Johann , DZIKOWSKI, Ron , NASEREDDIN, Abed

IPC分类号： C07D209/12

CPC分类号： C07D403/08 , A61P33/06 , C07D209/12 , C07D401/08 , C07D471/04

摘要： In a first aspect, the present invention relates to new compounds as depicted in formula (I). In particular, compounds according to the present invention are bisindolylcyclobuten-dione-based structures having antiprotozoal activity. In a further aspect, pharmaceutical compositions containing the same are provided as well as the use of the compounds and pharmaceutical compositions for the prophylaxis and treatment of parasite based diseases including malaria. Finally, methods for the treatment of parasite diseases including malaria are provided.