公开(公告)号：EP4311859A1

公开(公告)日：2024-01-31

申请号：EP22187293.0

申请日：2022-07-27

申请人： Technische Universität München

发明人： Masri, Mahmoud ,  Brück, Thomas

IPC分类号： C12P5/00 ,  C12P17/06 ,  C12P7/22

摘要： The present invention relates to a method for producing at least one target compound selected from a terpenoid, a phenolic compound, a vitamin, and a combination thereof. The present invention further relates to a composition comprising at least one target compound selected from a terpenoid, a phenolic compound, a vitamin, and a combination thereof.

公开(公告)号：EP4389905A1

公开(公告)日：2024-06-26

申请号：EP22215578.0

申请日：2022-12-21

申请人： Technische Universität München

发明人： Rerop, Zora Selina ,  Stellner, Nikolaus Isidor ,  Masri, Mahmoud ,  Brück, Thomas

IPC分类号： C12P7/6463 ,  C13K1/02 ,  C13K13/00

CPC分类号： C12P2203/0020130101 ,  C12P7/6463

摘要： The present invention relates to a method of reducing a salt content of a hydrolysate which comprises salt. The present invention further relates to a method of producing a target product, preferably a microbial oil, comprising providing a hydrolysate with reduced salt content and cultivating a microorganism, preferably an oleaginous microorganism, using a growth medium comprising the hydrolysate with reduced salt content.

公开(公告)号：EP4202043A1

公开(公告)日：2023-06-28

申请号：EP21217144.1

申请日：2021-12-22

申请人： Technische Universität München

发明人： Shaigani, Pariya ,  Brück, Thomas ,  Mehlmer, Norbert

IPC分类号： C12N9/22 ,  C12P7/64 ,  C12N15/52 ,  C12N15/90 ,  C12N15/11

摘要： The present invention relates to a method of genetically modifying a GC rich microorganism. The present invention further relates to a genetically modified GC rich microorganism. Furthermore, the present invention relates to a composition comprising a RNA-guided endonuclease, at least one guide RNA (gRNA), and optionally donor DNA. The present invention also relates to a method of preparing a target compound, e.g. an acetyl-CoA-based hydrophobic compound, and/or an oil having a specific fatty acid profile, e.g. high oleic oil, using a genetically modified GC rich microorganism.

公开(公告)号：EP3808440A1

公开(公告)日：2021-04-21

申请号：EP19203431.2

申请日：2019-10-15

申请人： Technische Universität München

发明人： Woortman, Dirk Volker ,  Brück, Thomas

IPC分类号： B01F13/08 ,  B01F13/00 ,  B01F3/04 ,  B01F15/00 ,  C12M1/02

摘要： Provided is a holder 10 for a magnetic agitator 12 which comprises a top section 14 which is configured to be attached to a vessel 18 , wherein the top section 14 is preferably configured to be attached to an aperture 16 of said vessel, a bottom section 24 which is configured to be immersed into a liquid 28 contained in said vessel 18 , and an elongate middle section 26 arranged between and connecting said bottom section 24 and said top section 14 , wherein said bottom section 24 forms at least one of a cage 30 and an annular guide 30a for said magnetic agitator 12 .