公开(公告)号：EP2155246A1

公开(公告)日：2010-02-24

申请号：EP07748678.5

申请日：2007-05-11

申请人： Temasek Life Sciences Laboratory Limited

发明人： LAU, Adeline Hui Ling ,  LAU, Jennifer Siew Kee ,  KWANG, Hwei-Sing

IPC分类号： A61K39/12 ,  C12N5/06 ,  C12N7/02

CPC分类号： C12N7/00 ,  C12N2750/10052

摘要： Continuous cell lines that are highly permissive to infection by porcine circovirus type 2 ('PCV2') are described. PCV2 is the causal agent of post-weaning multi-systemic wasting syndrome ('PMWS') in pigs. PMWS has emerged as a major disease that poses a significant threat to the economics of global swine industry. The highly permissive cell lines of this invention provide efficient and reliable sources of PCV2 for use in development of vaccines, therapies and diagnostic agents for PMWS.

摘要翻译： 描述了对猪圆环病毒2型（'PCV2'）感染高度宽容的连续细胞系。 PCV2是猪体内断奶后多系统消瘦综合征（'PMWS'）的致病因子。 PMWS已成为对全球猪业的经济构成重大威胁的主要疾病。 本发明的高度允许的细胞系提供了有效且可靠的PCV2来源，用于开发PMWS的疫苗，治疗和诊断剂。