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1.发明授权MONOCLONAL ANTIBODIES SPECIFIC TO HEMAGGLUTININ AND NEURAMINIDASE FROM INFLUENZA VIRUS H5-SUBTYPE OR N1-SUBTYPE AND USES THEREOF 有权血凝素和神经氨酸酶特异性单克隆抗体H5甲型类型下，N1下的流感病毒类型及其用途
公开(公告)号：EP2201039B1
公开(公告)日：2015-07-15
申请号：EP08830693.1
申请日：2008-09-12
发明人： QIAN, Hong Liang , HE, Fang , KWANG, Hwei-Sing
IPC分类号： C07K16/10 , A61K39/145 , A61P31/16 , C12N7/00 , G01N33/53 , G01N33/577
CPC分类号： C07K16/1018 , A61K2039/505 , C07K2317/34 , C07K2317/76 , C12N2760/16111 , G01N33/56983 , G01N2333/11
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2.发明授权PRODUCTION OF A HOMOGENEOUS CELL LINE HIGHLY PERMISSIVE TO PORCINE CIRCOVIRUS TYPE 2 (PCV2) INFECTION 有权是生产同质细胞系，高易感染猪肉-2型圆环病毒（PCV2）
公开(公告)号：EP2155246B1
公开(公告)日：2013-03-13
申请号：EP07748678.5
申请日：2007-05-11
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , C12N2750/10052
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3.发明授权MONOCLONAL ANTIBODIES SPECIFIC TO HEMAGGLUTININ FROM INFLUENZA VIRUS H5-SUBTYPE AND USES THEREOF 有权对于特殊H5血凝素单克隆抗体从分型流感病毒及其用途
公开(公告)号：EP2207804B1
公开(公告)日：2015-07-22
申请号：EP08830488.6
申请日：2008-08-26
申请人： Temasek Life Sciences Laboratory Limited , National Institute of Health Research and Development (NIHRD) - Ministry of Health of The Republic of Indonesia
IPC分类号： C07K16/10 , A61K39/145 , A61K39/42 , C12N7/00 , C12P21/00 , C12P21/08 , G01N33/53 , G01N33/569
CPC分类号： C07K16/1018 , A61K39/42 , C07K2317/24 , C07K2317/76 , C12N2760/16111 , G01N33/56983 , G01N2333/11
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4.发明公开PRODUCTION OF A HOMOGENEOUS CELL LINE HIGHLY PERMISSIVE TO PORCINE CIRCOVIRUS TYPE 2 (PCV2) INFECTION 有权产生高度允许感染2型环状感染（PCV2）感染的均质细胞系
公开(公告)号：EP2155246A1
公开(公告)日：2010-02-24
申请号：EP07748678.5
申请日：2007-05-11
CPC分类号： C12N7/00 , C12N2750/10052
摘要： Continuous cell lines that are highly permissive to infection by porcine circovirus type 2 ('PCV2') are described. PCV2 is the causal agent of post-weaning multi-systemic wasting syndrome ('PMWS') in pigs. PMWS has emerged as a major disease that poses a significant threat to the economics of global swine industry. The highly permissive cell lines of this invention provide efficient and reliable sources of PCV2 for use in development of vaccines, therapies and diagnostic agents for PMWS.
摘要翻译： 描述了对猪圆环病毒2型（'PCV2'）感染高度宽容的连续细胞系。 PCV2是猪体内断奶后多系统消瘦综合征（'PMWS'）的致病因子。 PMWS已成为对全球猪业的经济构成重大威胁的主要疾病。 本发明的高度允许的细胞系提供了有效且可靠的PCV2来源，用于开发PMWS的疫苗，治疗和诊断剂。
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5.发明公开MONOCLONAL ANTIBODIES SPECIFIC TO HEMAGGLUTININ FROM INFLUENZA VIRUS H5-SUBTYPE AND USES THEREOF 有权对于特殊H5血凝素单克隆抗体从分型流感病毒及其用途
公开(公告)号：EP2207804A1
公开(公告)日：2010-07-21
申请号：EP08830488.6
申请日：2008-08-26
申请人： Temasek Life Sciences Laboratory Limited , National Institute of Health Research and Development (NIHRD) - Ministry of Health of The Republic of Indonesia
IPC分类号： C07K16/10 , A61K39/145 , A61K39/42 , C12N7/00 , C12P21/00 , C12P21/08 , G01N33/53 , G01N33/569
CPC分类号： C07K16/1018 , A61K39/42 , C07K2317/24 , C07K2317/76 , C12N2760/16111 , G01N33/56983 , G01N2333/11
摘要： Monoclonal antibodies and related binding proteins that are specific for conformational epitopes of avian influenza virus K5 subtype hemagglutinin glycoprotein are provided. The antibodies can be used for the detection and treatment of H5 subtype AIV in specimens.
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6.发明公开MONOCLONAL ANTIBODIES SPECIFIC TO HEMAGGLUTININ AND NEURAMINIDASE FROM INFLUENZA VIRUS H5-SUBTYPE OR N1-SUBTYPE AND USES THEREOF 有权血凝素和神经氨酸酶特异性单克隆抗体H5甲型类型下，N1下的流感病毒类型及其用途
公开(公告)号：EP2201039A1
公开(公告)日：2010-06-30
申请号：EP08830693.1
申请日：2008-09-12
发明人： QIAN, Hong Liang , HE, Fang , KWANG, Hwei-Sing
IPC分类号： C07K16/10 , A61K39/145 , A61P31/16 , C12N7/00 , G01N33/53 , G01N33/577
CPC分类号： C07K16/1018 , A61K2039/505 , C07K2317/34 , C07K2317/76 , C12N2760/16111 , G01N33/56983 , G01N2333/11
摘要： Monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes or neuraminidase glycoprotein of N1 subtypes of avian influenza virus (AIV) are provided. The monoclonal antibodies and related binding proteins are useful for the detection of H5 and N1 subtypes of AIV, including H5N1 subtypes and provide means for the diagnosis, surveillance and treatment of dangerous viral infections.
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