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公开(公告)号:EP3761984A1
公开(公告)日:2021-01-13
申请号:EP19763756.4
申请日:2019-03-07
IPC分类号: A61K31/4985 , C07D498/04 , G01N33/50
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公开(公告)号:EP3761985A1
公开(公告)日:2021-01-13
申请号:EP19763857.0
申请日:2019-03-07
IPC分类号: A61K31/4985 , C07D498/04 , G01N33/50
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公开(公告)号:EP2710384A1
公开(公告)日:2014-03-26
申请号:EP12782510.7
申请日:2012-05-11
发明人: MERALI, Salim , MONCADA, Camilo , KELSEN, Steven, G. , BARRERO, Carlos, A. , PEREZ LEAL, Oscar, Mauricio
IPC分类号: G01N33/68
CPC分类号: G01N33/6875 , G01N33/577 , G01N2440/12 , G01N2800/122 , G01N2800/56 , H01J49/0027
摘要: Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a post-translational modification. In some embodiments, the histone protein is H2B, H3, H3.3 or H4. Kits for practicing the methods of diagnosis and/or staging are provided as well. Further provided is a method for treating COPD.
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公开(公告)号:EP2710384B1
公开(公告)日:2017-11-08
申请号:EP12782510.7
申请日:2012-05-11
发明人: MERALI, Salim , MONCADA, Camilo , KELSEN, Steven, G. , BARRERO, Carlos, A. , PEREZ LEAL, Oscar, Mauricio
IPC分类号: G01N33/68 , G01N33/577
CPC分类号: G01N33/6875 , G01N33/577 , G01N2440/12 , G01N2800/122 , G01N2800/56 , H01J49/0027
摘要: Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a post-translational modification. In some embodiments, the histone protein is H2B, H3, H3.3 or H4. Kits for practicing the methods of diagnosis and/or staging are provided as well. Further provided is a method for treating COPD.
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