专利检索 ap:("Temple University - Of The Commonwealth System of Higher Education") AND inv:"CHILDERS, Wayne, E." 第 1 页

1.

发明公开
NOVEL AMINOTHIAZOLE COMPOUNDS AND METHODS USING SAME 审中-公开

公开(公告)号：EP3324962A1

公开(公告)日：2018-05-30

申请号：EP16828552.6

申请日：2016-07-21

申请人： Temple University Of The Commonwealth System Of Higher Education

发明人： ISSA, Jean-Pierre, J. , ZHANG, Hanghang , ABU-GHARBIA, Magid , CHILDERS, Wayne, E. , MORTON, George, C.

IPC分类号： A61K31/427 , C07D417/02 , A61K31/36

CPC分类号： C07D417/14 , A61K31/427 , A61K31/706 , A61K45/06 , A61K2300/00 , A61P35/00 , C07D417/06

摘要： The present invention includes novel aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.

2.

发明公开
NOVEL BETA LACTAMS AS MODULATORS OF GLUTAMATE UPTAKE AND METHODS FOR USE THEREOF 审中-公开
标题翻译：新的β-内酰胺类以备使用谷氨酸记录和方法的调节剂THEREOF

公开(公告)号：EP3036219A2

公开(公告)日：2016-06-29

申请号：EP14807857.9

申请日：2014-06-04

申请人： Temple University Of The Commonwealth System Of Higher Education

发明人： ABOU-GHARBIA, Magid , CHILDERS, Wayne, E. , MARTINEZ, Rogelio, L. , RAMANJULU, Mercy, M. , BLASS, Benjamin, E.

IPC分类号： C07D205/08 , C07D403/06 , C07D471/08 , C07D487/08

CPC分类号： C07D403/06 , C07D205/08 , C07D471/08 , C07D487/08

摘要： Pharmaceutical compositions of the invention comprise compounds, compositions, methods useful for the treatment of drug addiction, drug withdrawal, and diseases or conditions that involve dysregulation of glutamate homeostasis in it etiology.

3.

发明公开
(S)-2-AMINO-6-((3-AMINOPROPYL)AMINO)HEXANOIC ACID (APL) FOR USE IN THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS (NASH), LIVER INFLAMMATION, HEPATOCELLULAR BALLOONING, LIVER FIBROSIS AND STEATOSIS 审中-公开

公开(公告)号：EP4138812A1

公开(公告)日：2023-03-01

申请号：EP21724981.2

申请日：2021-04-23

申请人： Temple University - Of The Commonwealth System of Higher Education

发明人： MERALI, Salim , CHILDERS, Wayne, E. , BARRERO, Carlos , MORTON, George, C. , RICO, Mario Cesar

IPC分类号： A61K31/198 , A61K45/06 , C07C229/08 , C07C229/26 , A61P1/16 , G01N33/50

4.

发明公开
COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE 审中-公开

公开(公告)号：EP3761984A1

公开(公告)日：2021-01-13

申请号：EP19763756.4

申请日：2019-03-07

申请人： Temple University - Of The Commonwealth System of Higher Education

发明人： MERALI, Salim , BARRERO, Carlos, A. , CHILDERS, Wayne, E. , MORTON, George, C.

IPC分类号： A61K31/4985 , C07D498/04 , G01N33/50

5.

发明公开
COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE 审中-公开

公开(公告)号：EP3761985A1

公开(公告)日：2021-01-13

申请号：EP19763857.0

申请日：2019-03-07

申请人： Temple University - Of The Commonwealth System of Higher Education

发明人： MERALI, Salim , BARRERO, Carlos, A. , CHILDERS, Wayne, E. , MORTON, George, C.

IPC分类号： A61K31/4985 , C07D498/04 , G01N33/50

6.

发明公开
NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE 审中-公开

公开(公告)号：EP3571196A1

公开(公告)日：2019-11-27

申请号：EP18741448.7

申请日：2018-01-19

申请人： Temple University Of The Commonwealth System Of Higher Education

发明人： CHILDERS, Wayne, E. , ABOU-GHARBIA, Magid, A. , MORTON, George, C. , ISSA, Jean-Pierre, J. , ZHANG, Hanghang

IPC分类号： C07D413/14 , C07D471/04