公开(公告)号：EP2951282B1

公开(公告)日：2019-05-08

申请号：EP14706712.8

申请日：2014-01-29

申请人： The Charles Stark Draper Laboratory, Inc. ,  Massachusetts Institute of Technology

发明人： CUIFFI, Joseph Dennis ,  MESCHER, Mark Joseph ,  COPPETA, Jonathan Robert ,  INMAN, Samuel Walker ,  SPENCER, Abigail June ,  NGUYEN, Transon Van ,  BORENSTEIN, Jeffrey T.

IPC分类号： C12M3/00 ,  C12M1/32 ,  C12M1/00 ,  C12M1/34

公开(公告)号：EP2951282A1

公开(公告)日：2015-12-09

申请号：EP14706712.8

申请日：2014-01-29

申请人： The Charles Stark Draper Laboratory, Inc. ,  Massachusetts Institute of Technology

发明人： CUIFFI, Joseph Dennis ,  MESCHER, Mark Joseph ,  COPPETA, Jonathan Robert ,  INMAN, Samuel Walker ,  SPENCER, Abigail June ,  NGUYEN, Transon Van ,  BORENSTEIN, Jeffrey T.

IPC分类号： C12M3/00 ,  C12M1/32 ,  C12M1/00 ,  C12M1/34

CPC分类号： C12M21/08 ,  C12M23/12 ,  C12M23/44 ,  C12M29/00 ,  C12M29/04 ,  C12M29/12 ,  C12M35/08 ,  C12M41/00 ,  C12M41/12 ,  C12N5/0062 ,  C12N5/0602 ,  C12N5/0697

摘要： The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the organ systems are fluidically connected with a constant-volume pump.