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1.发明授权
公开(公告)号：EP2436787B1
公开(公告)日：2016-01-20
申请号：EP11196265.0
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
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2.发明授权
公开(公告)号：EP2436786B1
公开(公告)日：2014-04-16
申请号：EP11196264.3
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
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3.发明授权Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases 有权用于诊断和治疗结肠相关疾病的基于微RNA的方法和组合物
公开(公告)号：EP2455493B1
公开(公告)日：2014-01-08
申请号：EP11196250.2
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
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4.发明公开Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases 有权用于诊断和治疗结肠相关疾病的基于微RNA的方法和组合物
公开(公告)号：EP2455494A1
公开(公告)日：2012-05-23
申请号：EP11196253.6
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
摘要翻译： 本发明提供了诊断和治疗结肠癌的新方法和组合物。 本发明还提供了鉴定肿瘤发生抑制剂的方法。
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5.发明公开Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases 有权用于诊断和治疗结肠相关疾病的基于微RNA的方法和组合物
公开(公告)号：EP2455493A1
公开(公告)日：2012-05-23
申请号：EP11196250.2
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis,
摘要翻译： 本发明提供了诊断和治疗结肠癌的新方法和组合物。 本发明还提供了鉴定肿瘤发生抑制剂的方法，
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6.发明公开MIR-21 for diagnosing poor survival prognosis colon adenocarcinoma 有权Micro-ARN-21 zur Diagnose von Darm Adenokarzinom mit schlechter Uberlebensprognose。
公开(公告)号：EP2436787A1
公开(公告)日：2012-04-04
申请号：EP11196265.0
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
摘要翻译： 本发明提供了用于诊断和治疗结肠癌的新型方法和组合物。 本发明还提供鉴定肿瘤发生抑制剂的方法。
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7.发明公开MIR-29a for diagnosing poor survival prognosis colon adenocarcinoma. 有权微型ARN-29a zur诊断von Darm Adenokarzinom mit schlechter Uberlebensprognose。
公开(公告)号：EP2436785A1
公开(公告)日：2012-04-04
申请号：EP11196262.7
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
摘要翻译： 本发明提供了用于诊断和治疗结肠癌的新型方法和组合物。 本发明还提供鉴定肿瘤发生抑制剂的方法。
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8.发明授权Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases 有权方法和组合物以微RNA碱基对的疾病与结肠有关的诊断和治疗
公开(公告)号：EP2369017B8
公开(公告)日：2014-03-12
申请号：EP11170608.1
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Harris, Curtis , Schetter, Aaron
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
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9.发明授权
公开(公告)号：EP2455494B1
公开(公告)日：2013-12-18
申请号：EP11196253.6
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
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10.发明公开Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases 有权方法和组合物以微RNA碱基对的疾病与结肠有关的诊断和治疗
公开(公告)号：EP2455492A1
公开(公告)日：2012-05-23
申请号：EP11196190.0
申请日：2007-07-12
申请人： The Ohio State University Research Foundation , The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
发明人： Croce, Carlo , Schetter, Aaron , Harris, Curtis
IPC分类号： C12Q1/68
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12Q1/6809 , C12Q1/6886 , C12Q2525/207 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/178 , Y10T436/143333
摘要： The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis,
摘要翻译： 本发明提供了用于结肠癌的诊断和治疗的新的方法和组合物。 因此本发明提供鉴定肿瘤发生抑制剂的方法，
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